175735-53-2

Basic information

• Product Name: (2S,3R,4S)-(N-Benzyloxycarbonyl)-6,6-dicarboxy-3,4-methano-L-proline trimethyl ester
• CAS NO: 175735-53-2
• Molecular Weight: 391.378
• Mol File: 175735-53-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3R,4S)-(N-Benzyloxycarbonyl)-6,6-dicarboxy-3,4-methano-L-proline trimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R,4S)-(N-Benzyloxycarbonyl)-6,6-dicarboxy-3,4-methano-L-proline trimethyl ester(175735-53-2)
• EPA Substance Registry System: (2S,3R,4S)-(N-Benzyloxycarbonyl)-6,6-dicarboxy-3,4-methano-L-proline trimethyl ester(175735-53-2)

Safety Data

• Hazardous Substances Data: 175735-53-2(Hazardous Substances Data)

Upstream product

• 6773-29-1 dimethyl diazomalonate 
• 5211-24-5 (2S)-2,5-dihydro-1H-pyrrole-1,2-dicarboxylic acid 2-methyl 1-(phenylmethyl) ester 

Relevant articles and documents

Synthesis of 6,6-dicarboxy-3,4-methano-L-proline, a new constrained glutamate analog endowed with neuroprotective properties

6,6-Dicarboxy-3,4-methano-L-proline (L-DCMP, 7) has been prepared by the rhodium(II)acetate dimer catalyzed decomposition of dimethyl diazomalonate in the presence of a 3,4-didehydroproline derivative. When evaluated against NMDA- and kainate-induced toxicity in cultured cortical neurons, L-DCMP (7) exhibited good neuroprotective activity.