175844-86-7Relevant academic research and scientific papers
Synthesis of 5-phosphate-D-arabinohydroxamic acid, a potent transition state analogue inhibitor of 6-phosphate-D-glycose isomerases
Bonnette,Salmon,Gaudemer
, p. 1221 - 1224 (2007/10/03)
The first hydroxamate-based and potent transition state analogue (TSA) inhibitor of 6-phosphate-D-glucose isomerases, 5-phosphate-D-arabinohydroxamic acid 3, has been synthesized by conversion of D-arabinose to a protected derivative of 5-phosphate-D-arabinonic acid and introduction of the hydroxamine group by coupling with O-benzylhydroxylamine.
