175873-08-2

Basic information

• Product Name: 4-[(S)-3-AMINO-2-OXOPYRROLIDIN-1-YL)BENZONITRILE HYDROCHLORIDE
• Synonyms: 4-[(S)-3-AMINO-2-OXOPYRROLIDIN-1-YL)BENZONITRILE HYDROCHLORIDE
• CAS NO: 175873-08-2
• Molecular Formula: C11H11 N3 O . Cl H
• Molecular Weight: 237.69
• Mol File: 175873-08-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-[(S)-3-AMINO-2-OXOPYRROLIDIN-1-YL)BENZONITRILE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(S)-3-AMINO-2-OXOPYRROLIDIN-1-YL)BENZONITRILE HYDROCHLORIDE(175873-08-2)
• EPA Substance Registry System: 4-[(S)-3-AMINO-2-OXOPYRROLIDIN-1-YL)BENZONITRILE HYDROCHLORIDE(175873-08-2)

Safety Data

• Hazardous Substances Data: 175873-08-2(Hazardous Substances Data)

Upstream product

• 175873-04-8 N-(4-cyanophenyl)-3(S)-[[(1,1-dimethylethoxy)carbonyl]amino]pyrrolidin-2-one 
• 167834-07-3 N-(4-cyanophenyl)-4-hydroxy-2-[(1,1-dimethyl)ethoxycarbonylamino]butanamide 
• 1972-28-7 diethylazodicarboxylate 

Downstream Products

• 163250-90-6 Ethyl 3-[[[[1-[4-(aminoiminomethyl)phenyl]-2-oxo-3-pyrrolidinyl]amino]carbonyl]amino]propionate 

Relevant articles and documents

Process for the preparation of 3-amino-2-oxo-pyrrolidines, novel intermediates and their use

The present invention relates to a process for the preparation of γ-lactams of the general formula I The invention relates also to novel advantageous intermediates of the general formulae V, IV and II and their salts and their use. The compounds of the ge

Procedure for the manufacture of 3-amino-2-oxo-pyrrolidines, new intermediates and their use

The invention is directed to a process for the preparation of lactams of Formula I. It is further directed to new advantageous intermediates of Formula II and the use thereof. By the cyclization of compounds of Formula II, compounds of Formula I are obtained.

Process for the preparation of a 2-oxopyrrolidine compound

A process for producing a lactam of the formula STR1 wherein 2-bromo-4 chloro butyryl bromide or 2,4-dibromo butyryl bromide is coupled with 4-aminobenzonitrile to produce 4-(2,4-bromobutyrylamino)-benzonitrile, which is combined with sodium hydroxide, po

Platelet aggregation inhibitors

This invention relates to compounds having the following formula STR1 or a pharmaceutically acceptable salt thereof which are useful in the inhibition of platelet aggregation, to pharmaceutical compositions of such phenylamidines derivatives, and to a method of inhibiting platelet aggregation in mammals by administering such compounds and compositions.

Process for the preparation of amidino phenyl pyrrolidine β-alanine urea analogs

The invention herein is directed to a process for producing a lactam of the formula STR1 from a methionine analog of the formula STR2 by treating the methionine analog with trimethylsulfonium halide or trimethylsulfoxonium halide in the presence of a base in a suitable aprotic solvent. The invention herein is further directed to the preparation of amidinophenyl pyrrolidinyl β-alanine urea analogs using such methionine and lactam compounds as intermediates, which β-alanine urea analogs are useful as antithrombotics.