175873-10-6

Basic information

• Product Name: ETHYL 3-(3-{(S)-1-[4-(N''2-HYDROXYAMIDINO)PHENYL]-2-OXOPYRROLIDIN-3-YL}UREIDO)PROPIONATE
• Synonyms: ETHYL 3-(3-{(S)-1-[4-(N''2-HYDROXYAMIDINO)PHENYL]-2-OXOPYRROLIDIN-3-YL}UREIDO)PROPIONATE
• CAS NO: 175873-10-6
• Molecular Formula: C₁₇H₂₃N₅O₅
• Molecular Weight: 0
• Mol File: 175873-10-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ETHYL 3-(3-{(S)-1-[4-(N''2-HYDROXYAMIDINO)PHENYL]-2-OXOPYRROLIDIN-3-YL}UREIDO)PROPIONATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 3-(3-{(S)-1-[4-(N''2-HYDROXYAMIDINO)PHENYL]-2-OXOPYRROLIDIN-3-YL}UREIDO)PROPIONATE(175873-10-6)
• EPA Substance Registry System: ETHYL 3-(3-{(S)-1-[4-(N''2-HYDROXYAMIDINO)PHENYL]-2-OXOPYRROLIDIN-3-YL}UREIDO)PROPIONATE(175873-10-6)

Safety Data

• Hazardous Substances Data: 175873-10-6(Hazardous Substances Data)

Upstream product

• 175873-09-3 3-[[[[1-(4-cyanophenyl)-2-oxo-3(S)-pyrrolidinyl]amino]carbonyl]amino]propionate ethyl ester 

Relevant articles and documents

Process for the preparation of amidino phenyl pyrrolidine β-alanine urea analogs

The invention herein is directed to a process for producing a lactam of the formula STR1 from a methionine analog of the formula STR2 by treating the methionine analog with trimethylsulfonium halide or trimethylsulfoxonium halide in the presence of a base in a suitable aprotic solvent. The invention herein is further directed to the preparation of amidinophenyl pyrrolidinyl β-alanine urea analogs using such methionine and lactam compounds as intermediates, which β-alanine urea analogs are useful as antithrombotics.