175891-78-8

Basic information

• Product Name: Cyclopentanecarboxaldehyde, 2-methyl-5-(1-methylethylidene)-, (1R-cis)- (9CI)
• Synonyms: Cyclopentanecarboxaldehyde, 2-methyl-5-(1-methylethylidene)-, (1R-cis)- (9CI)
• CAS NO: 175891-78-8
• Molecular Formula: C10H16O
• Molecular Weight: 152.23344
• Product Categories: ALDEHYDE
• Mol File: 175891-78-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclopentanecarboxaldehyde, 2-methyl-5-(1-methylethylidene)-, (1R-cis)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanecarboxaldehyde, 2-methyl-5-(1-methylethylidene)-, (1R-cis)- (9CI)(175891-78-8)
• EPA Substance Registry System: Cyclopentanecarboxaldehyde, 2-methyl-5-(1-methylethylidene)-, (1R-cis)- (9CI)(175891-78-8)

Safety Data

• Hazardous Substances Data: 175891-78-8(Hazardous Substances Data)

Upstream product

• 7712-70-1 ((1S)-2-isopropylidene-5t-methyl-cyclopent-r-yl)-methanol 
• 54712-95-7 (R)-ethyl 2-methyl-5-(propan-2-ylidene)cyclopentanecarboxylate 
• 623935-92-2 ethyl (2R)-2-methyl-5-(propan-2-ylidene)cyclopentanecarboxylate 

Relevant articles and documents

Studies on Horner-Wadsworth-Emmons reaction in base sensitive ketones: Synthesis of (-)-mitsugashiwalactone and formal synthesis of (+)-iridomyrmecin, (-)-isoiridomyrmecin and (+)-teucriumlactone

The effect of different bases in promoting Horner-Wadsworth-Emmons (HWE) reaction on enolisable cyclopentanones is investigated. NaH is found to be suitable for the intermolecular reaction and DBU/LiCl is optimal for the intramolecular variation. The HWE approach is employed for the enantioselective synthesis of iridoid cyclopentapyranones of type-I (4, 16, 52) and type-II (5, 36).