175908-27-7Relevant academic research and scientific papers
Synthesis of 6-substituted 1-deazapurine 2'-deoxyribonucleosides
Wenzel,Seela
, p. 169 - 178 (1996)
The synthesis of 6-substituted 1-deazapurine 2'-deoxyribonucleosides is described. Glycosylation of the 1-deazapurine (imidazo[4,5-b]pyridine) anions with the α-D-halogenose 5 gives stereoselectively N7- and N9-regioisomers. 1H-NMR NOE and 13C-NMR spectroscopy are used for unambiguous assignment of isomers, and 15N-NMR chemical shifts are correlated with σ(para) Hammett constants and point charges.
