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175965-83-0

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175965-83-0 Usage

General Description

Pyridine, 2-fluoro-4-methoxy- (9CI) is a chemical compound that belongs to the class of pyridine derivatives. It is characterized by the presence of a pyridine ring with a fluorine atom and a methoxy group attached at the 2 and 4 positions, respectively. Pyridine, 2-fluoro-4-methoxy- (9CI) is used in the field of organic chemistry and pharmaceutical research as a building block for the synthesis of various biologically active compounds. Its unique structure and functional groups make it a valuable intermediate in the development of drugs and agrochemicals. Additionally, it may also have potential applications in materials science and other industrial processes.

Check Digit Verification of cas no

The CAS Registry Mumber 175965-83-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,9,6 and 5 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 175965-83:
(8*1)+(7*7)+(6*5)+(5*9)+(4*6)+(3*5)+(2*8)+(1*3)=190
190 % 10 = 0
So 175965-83-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H6FNO/c1-9-5-2-3-8-6(7)4-5/h2-4H,1H3

175965-83-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Fluoro-4-methoxypyridine

1.2 Other means of identification

Product number -
Other names PYRIDINE,2-FLUORO-4-METHOXY

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:175965-83-0 SDS

175965-83-0Relevant articles and documents

PhenoFluorMix: Practical chemoselective deoxyfluorination of phenols

Fujimoto, Teppei,Ritter, Tobias

supporting information, p. 544 - 547 (2015/03/05)

A practical deoxyfluorination with novel deoxyfluorinating reagent PhenoFluorMix, a mixture of N,N'-1,3-bis(2,6-diisopropylphenyl)chloroimidazolium chloride and CsF, is presented. PhenoFluorMix overcomes the challenges associated with hydrolysis of PhenoFluor. PhenoFluorMix does not hydrolyze, is readily available on decagram scale, and is storable in air. In this paper, we demonstrate the practicality of the reagent and exhibit the deoxyfluorination of a variety of phenols and heterocycles.

Selective C-H fluorination of pyridines and diazines inspired by a classic amination reaction

Fier, Patrick S.,Hartwig, John F.

, p. 956 - 960 (2013/12/04)

Fluorinated heterocycles are prevalent in pharmaceuticals, agrochemicals, and materials. However, reactions that incorporate fluorine into heteroarenes are limited in scope and can be hazardous. We present a broadly applicable and safe method for the site-selective fluorination of a single carbon-hydrogen bond in pyridines and diazines using commercially available silver(II) fluoride. The reactions occur at ambient temperature within 1 hour with exclusive selectivity for fluorination adjacent to nitrogen. The mild conditions allow access to fluorinated derivatives of medicinally important compounds, as well as a range of 2-substituted pyridines prepared by subsequent nucleophilic displacement of fluoride. Mechanistic studies demonstrate that the pathway of a classic pyridine amination can be adapted for selective fluorination of a broad range of nitrogen heterocycles.

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