175981-07-4

Upstream product

• 175980-94-6 Thexyldimethylsilyl 2-O-benzoyl-4,6-O-benzylidene-3-thio-β-D-galactopyranoside 
• 175980-95-7 Acetic acid (2S,3R,4R,5S,6S)-3-acetoxy-5-(4-methoxy-benzyloxy)-2-methyl-6-(2,2,2-trichloro-acetimidoyloxy)-tetrahydro-pyran-4-yl ester 
• 613-90-1 benzoyl cyanide 
• 108182-34-9 allyl 3,4-di-O-isopropylidene-α-L-fucopyranoside 
• 824-94-2 p-methoxybenzyl chloride 
• 175981-03-0 allyl 2-O-(p-methoxybenzyl)-3,4-O-isopropylidene-α-L-fucopyranoside 
• 175980-93-5 (2S,4aR,6S,7R,8R,8aR)-6-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine-7,8-diol 
• 175981-05-2 Acetic acid (2S,3R,4R,5S,6R)-3-acetoxy-6-hydroxy-5-(4-methoxy-benzyloxy)-2-methyl-tetrahydro-pyran-4-yl ester 
• 175981-04-1 allyl 3,4-di-O-acetyl-2-O-(4-methoxybenzyl)-α-L-fucopyranoside 
• 175981-00-7 Thexyldimethylsilyl 2-O-benzoyl-4,6-O-benzylidene-3-O-chloroacetyl-β-D-galactopyranoside 
• 175981-01-8 Thexyldimethylsilyl 2-O-benzoyl-4,6-O-benzylidene-β-D-galactopyranoside 
• 175981-02-9 Thexyldimethylsilyl 2-O-benzoyl-4,6-O-benzylidene-β-D-gulopyranoside 

Downstream Products

• 175981-08-5 Thexyldimethylsilyl 2-O-benzoyl-4,6-O-benzylidene-3-S-(2,3,4-tri-O-acetyl-α-L-fucopyranosyl)-3-thio-β-D-galactopyranoside 
• 175981-10-9 Thexyldimethylsilyl 4-S-acetyl-2,6-di-O-benzoyl-3-S-(2,3,4-tri-O-acetyl-α-L-fucopyranosyl)-3,4-dithio-β-D-glucopyranoside 
• 175981-12-1 Heptyl 4-S-acetyl-2,6-di-O-benzoyl-3-thio-(2,3,4-tri-O-acetyl-α-L-fucopyranosyl)-1,3,4-trithio-β-D-glucopyranoside 
• 175980-99-1 Heptyl S-(2,3,4-tri-O-acetyl-α-L-fucopyranosyl)-(1->3)-2,6-di-O-benzoyl-4-thio-β-D-glucopyranoside 
• 175980-97-9 Thexyldimethylsilyl 2,6-di-O-benzoyl-3-S-(2,3,4-tri-O-acetyl-α-L-fucopyranosyl)-3-thio-β-D-galactopyranoside 

Relevant academic research and scientific papers

Synthesis of a thio-linked analogue of sialyl Lewis X

Thiolinked sialyl Lewis X analogue 2 was obtained from neuraminic acid, D-galactose, and L-fucose. Galactose was transformed into 3-thiogalactose building block 6 and also into the required 3,4-dithioglucose moiety. Thioglycoside bond formation was performed via base-promoted S-glycosylation [Neu5Acα(2-3S)Gal and Galβ(1-4S)Glc linkages] and via acid catalyzed S-glycosylation [Fucα(1-3S)Glc and Glcβ-(1-1S)heptyl linkages].