176020-22-7Relevant academic research and scientific papers
Synthesis of α-galactosyl ceramide and the related glycolipids for evaluation of their activities on mouse splenocytes
Fan, Gang-Ting,Pan, Yi-Shin,Lu, Kuo-Cheng,Cheng, Yu-Pei,Lin, Wan-Chen,Lin, Steven,Lin, Chun-Hung,Wong, Chi-Huey,Fang, Jim-Min,Lin, Chun-Cheng
, p. 1855 - 1862 (2007/10/03)
Phytosphingosine and its short-chain analog were efficiently synthesized with 19% overall yield in 10 steps, respectively, starting from an inexpensive d-lyxose. Galactosyl donors of sulfide and phosphite types bearing benzoyl protecting groups of 4- and
Practical Total Synthesis of (2S,3S,4R)-1-O-(α-D-Galactopyranosyl)-N-hexacosanoyl-2-amino-1,3,4- octadecanetriol, the Antitumorial and Immunostimulatory α-Galactosylceramide, KRN7000
Morita, Masahiro,Sawa, Eiji,Yamaji, Kazuo,Sakai, Teruyuki,Natori, Takenori,Koezuka, Yasuhiko,Fukushima, Hideaki,Akimoto, Kohji
, p. 288 - 292 (2007/10/03)
A practical total synthesis of (2S,3S,4A)-1-O-(α-D-galactopyranosyl)-N-hexacosanoyl-2-amino-1,3,4- octadecanetriol (KRN7000), an antitumorial and immunostimulatory glycosphingolipid derived from agelasphins, was achieved in 14 steps starting from D-lyxose in a 16% overall yield.
