176021-32-2

Basic information

• Product Name: (+)-(R)-2-(4-Chlorothiophenoxy)propanoic acid
• CAS NO: 176021-32-2
• Molecular Weight: 216.688
• Mol File: 176021-32-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (+)-(R)-2-(4-Chlorothiophenoxy)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(R)-2-(4-Chlorothiophenoxy)propanoic acid(176021-32-2)
• EPA Substance Registry System: (+)-(R)-2-(4-Chlorothiophenoxy)propanoic acid(176021-32-2)

Safety Data

• Hazardous Substances Data: 176021-32-2(Hazardous Substances Data)

Upstream product

• 18518-85-9 ethyl 2-((4-chlorophenyl)thio)propanoate 
• 106-54-7 p-Chlorothiophenol 
• 18527-12-3 2-<(4-chlorophenyl)thio>propionic acid 
• 103247-65-0 2-<(4-Chlorphenyl)thio>-propansaeuremethylester 

Relevant articles and documents

Microbial deracemization of α-substituted carboxylic acids: Control of the reaction path

A novel approach to preparing optically active α-substituted carboxylic acids using the whole cells of Nocardia diaphanozonaria JCM 3208 is described. When 2-phenylthiopropanoic acid and 2-methyl-3-phenylpropanoic acid were subjected to the reaction under aerobic conditions, the oxidation reaction proceeded preferentially rather than deracemization of these substrates. Herein, we report the design of reaction conditions to increase the deracemization activity in preference to oxidation reactions. In addition, we have successfully detected a metabolic intermediate in the reaction mixture of 2-methyl-3-phenylpropanoic acid, which indicates that the deracemization is a competitive reaction against the α-oxidation pathway of fatty acid metabolism.

Differential eudismic ratios in the antagonism of human platelet function by phenoxy- and thiophenoxyacetic acids

The antilipidemic drug clofibric acid (CPIB) exhibits antiplatelet effects. In order to examine the role of enantioselectivity and hydrophobicity, the mono(desmethyl) enantiomers of 2-(4-chlorophenoxy)propanoic acid (CPPA), related butanoate homologs, 2-(