176040-34-9

Basic information

• Product Name: 1H-Pyrrolizine-1-carbonitrile,hexahydro-3-oxo-,cis-(9CI)
• Synonyms: 1H-Pyrrolizine-1-carbonitrile,hexahydro-3-oxo-,cis-(9CI)
• CAS NO: 176040-34-9
• Molecular Formula: C8H10N2O
• Molecular Weight: 0
• Product Categories: PYRROLIDINE
• Mol File: 176040-34-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Pyrrolizine-1-carbonitrile,hexahydro-3-oxo-,cis-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolizine-1-carbonitrile,hexahydro-3-oxo-,cis-(9CI)(176040-34-9)
• EPA Substance Registry System: 1H-Pyrrolizine-1-carbonitrile,hexahydro-3-oxo-,cis-(9CI)(176040-34-9)

Safety Data

• Hazardous Substances Data: 176040-34-9(Hazardous Substances Data)

Upstream product

• 143-33-9 sodium cyanide 
• 113089-35-3 (1R,8S)-1-mesyloxy-pyrrolizidin-3-one 
• 68-95-1 (S)-acetylproline 
• 161691-20-9 (S)-1-acetyl-N-methoxy-N-methylpyrrolidine-2-carboxamide 
• 150884-75-6 (S)-tetrahydro-1H-pyrrolizine-1,3(2H)-dione 
• 108910-03-8 (1R,7aS)-1-hydroxytetrahydro-1H-pyrrolizin-3(2H)-one 

Downstream Products

• 526-64-7 laburnine 

Relevant articles and documents

An efficient route to the pyrrolizidine ring system via an N-acyl anion cyclisation process

An enantioselective route to the pyrrolizidine ring system has been developed which uses an N-acyl anion cyclisation reaction as the key step. This methodology has provided the natural pyrrolizidines (-)-(1R, 8S)-1-hydroxy-pyrrolizidine 7, (-)-pyrrolizidin-1-ene-3-one 9 and (±)-trachelanthamidine 14. Extension of the process to an N-propionyl substrate provides ready access to a series of 2-methyl pyrrolizidines.