17607-02-2

Usage

Uses

Used in Pharmaceutical Industry:
1-Imidazolidinecarboxylic acid, 2-oxois used as an intermediate in the biosynthesis of histidine, an essential amino acid, for the development of pharmaceutical products.
Used in Cosmetic Industry:
1-Imidazolidinecarboxylic acid, 2-oxois used as a skin conditioning agent for its ability to improve skin texture and appearance.
Used in Antioxidant Formulations:
1-Imidazolidinecarboxylic acid, 2-oxois used as an antioxidant in cosmetic products to protect the skin from oxidative stress and environmental damage.

Upstream product

• 41730-78-3 1-methoxycarbonyl-2-imidazolidinone 

Downstream Products

• 120-93-4 imidazolidone 
• 13214-53-4 2-oxoimidazolidine-1-carbonyl chloride 

Relevant academic research and scientific papers

Solvent-accelerated decarboxylation of N-carboxy-2-imidazolidinone. Implications for stability of intermediates in biotin-dependent carboxylations

The decarboxylation of N-carboxy-2-imidazolidinone has previously been established as a model for the transfer of carbon dioxide from N(1')-carboxybiotin. The present paper reports the pH-dependence of the reaction as well as the acceleration of the reaction in methanol and in acetonitrile. These results suggest that enzymic reactions of N(1')-carboxybiotin in a hydrophobic active site with decreased hydrogen bonding can be rapid if the energy of desolvation is compensated by the energy made available by association of the substrate and protein. In addition, a report on the decarboxylation of N-carboxy-2-imidazolidinone in organic solvents containing macrocycles (Kluger, R.; Tsao, B.J. Am. Chem. Soc. 1993, 115, 2089-90) must be reinterpreted on the basis of the inherent instability of the substrate under the reaction conditions.