17613-44-4

Usage

Derivative of

Phenanthridin-6(5H)-one

Contains

An amino group

Potential applications

Medicinal chemistry

Biological activity

May be studied for its potential therapeutic uses

Research interest

Drug development and discovery

Industrial and research applications

Synthesis of other organic compounds

Further studies

Likely to reveal more about potential uses and properties

Upstream product

• 85008-21-5 phenanthridine; nitrate 
• 17726-57-7 5H-phenanthridin-6-one-1-carboxylic acid 
• 220356-50-3 1-nitrophenanthridine 
• 6223-83-2 9-oxo-9H-fluorene-4-carboxylic acid 
• 26690-02-8 1-nitro-phenanthridin-6-ol 

Relevant academic research and scientific papers

INVESTIGATION OF PHENANTHRIDONE AND DIOXOTETRAHYDRODIAZAPYRENE. 4. SYNTHESIS OF AMINO-SUBSTITUTED PHENANTHRIDONES and DIOXOTETRAHYDRODIAZAPYRENES

The corresponding mono-, di-, and triamino derivatives substituted in the 2, 4, and 8 positions of the phenanthridone ring were obtained by reduction of mono-, di-, and trinitro-substituted phenanthridone (I), phenanthridone-10-carboxylic acid (II), phenanthridone-1-carboxylic acid (III), 4H-cyclopentaphenanthridine-5,9-dione (IV), 4H-cyclopentaphenanthridin-5-one (V), 5,10-dioxo-4,5,9,10-tetrahydro-4,9-diazapyrene(VI), and 5,9-dioxo-4,5,9,10-tetrahydro-4,10-diazapyrene (VII) with powdered iron in an electrolyte medium, with hydrogen in the presence of a nickel catalyst, or with stannous chloride.The 2,4,7,9-tetraamino derivative of VI was similarly obtained. 1-Amino, 7-amino-, and 10-aminophenanthridones were obtained by the Schmidt reaction from the corresponding carboxylic acids. 1,10-Diamino- and 3,8-diaminophenanthridones were similarly obtained from the corresponding aminofluorenones.