17616-24-9

Usage

Uses

Used in Pharmaceutical Research:
ETHYL-D5-AMINE is used as a precursor in the synthesis of pharmaceuticals for its ability to provide insights into the molecular interactions and dynamics of drug candidates. The deuterated version aids in the elucidation of the compound's structure and function, which is crucial for drug development.
Used in Agrochemical Research:
In agrochemical research, ETHYL-D5-AMINE serves as a precursor for the synthesis of agrochemicals, helping to understand the interactions of these compounds with biological systems and the environment. The deuterium labeling allows for more accurate tracking and analysis of the compound's behavior.
Used in Advanced Material Synthesis:
ETHYL-D5-AMINE is utilized as a building block in the development of advanced materials, where its deuterated nature can enhance the understanding of material properties and performance.
Used in Nuclear Magnetic Resonance (NMR) Spectroscopy:
ETHYL-D5-AMINE is used as a deuterated standard or as a labeled compound in NMR spectroscopy for its ability to improve the resolution and sensitivity of the technique. The presence of deuterium atoms in the molecule allows researchers to study the compound's behavior in greater detail, which is essential for characterizing complex chemical and biological systems.
Used in Chemical Kinetics Studies:
ETHYL-D5-AMINE is employed in chemical kinetics studies to investigate reaction mechanisms and rates. The deuterium isotope effect can provide valuable information on the dynamics of chemical reactions, helping to elucidate the underlying processes and improve the understanding of reaction pathways.
Used in Environmental Research:
In environmental research, ETHYL-D5-AMINE can be used to study the fate and transport of ethylamine and its derivatives in the environment. The deuterium labeling allows for the tracking of the compound and its metabolites, providing insights into their behavior and potential impacts on ecosystems.

InChI:InChI=1/C2H7N/c1-2-3/h2-3H2,1H3/i1D3,2D2

Upstream product

• 2206-26-0 [D₃]acetonitrile 
• 121195-20-8 -ethyl phthalimide 

Relevant academic research and scientific papers

Synthesis of bisaramil labelled with carbon-14 and deuterium

[6,8-14C2]-Bisaramil: 3-methyl-7-ethyl-9α-(4-chlorobenzoyloxy)-3,7-diazabicyclo/3.3.1./nona ne-[6,8-14C2]monohydrochloride and [7-N-D5-ethyl]-Bisaramil: 3-methyl-7-[D5-ethyl]-9α-(4-chlorobe

Quantification of four major metabolites of embryotoxic N -methyl- and N -ethyl-2-pyrrolidone in human urine by cooled-injection gas chromatography and isotope dilution mass spectrometry

N-Methyl- and N-ethyl-2-pyrollidone (NMP and NEP) are frequently used industrial solvents and were shown to be embryotoxic in animal experiments. We developed a sensitive, specific, and robust analytical method based on cooled-injection (CIS) gas chromatography and isotope dilution mass spectrometry to analyze 5-hydroxy-N-ethyl-2-pyrrolidone (5-HNEP) and 2-hydroxy-N- ethylsuccinimide (2-HESI), two newly identified presumed metabolites of NEP, and their corresponding methyl counterparts (5-HNMP, 2-HMSI) in human urine. The urine was spiked with deuterium-labeled analogues of these metabolites. The analytes were separated from urinary matrix by solid-phase extraction and silylated prior to quantification. Validation of this method was carried out by using both, spiked pooled urine samples and urine samples from 56 individuals of the general population with no known occupational exposure to NMP and NEP. Interday and intraday imprecision was better than 8% for all metabolites, while the limits of detection were between 5 and 20 μg/L depending on the analyte. The high sensitivity of the method enables us to quantify NMP and NEP metabolites at current environmental exposures by human biomonitoring.

The Collision-Induced Dissociations of Deprotonated Amines in the Gas Phase

The major collision-induced fragmentations of deprotonated primary and secondary amines are best rationalized as proceeding through the intermediacy of ion complexes.For example, the characteristic fragmentation of deprotonated ethylamine is MeCH2NH- -> -(CH2=NH)> -> CH2N- + CH4 Secondary alkylamines behave in a similar fashion.The occurrence of proton transfer as a prelude to fragmentation is rare: the only example observed in this study is the probable reaction PhNEt ->-> PhNHCHMe -> -> -> C7H6N- + CH4 which is preceded or accompanied by proton transfer between the methylene and phenyl substituents.Deprotonated aniline undergoes specific elimination of CNH from the 1-position to form the cyclopentadienyl anion.Finally, retro reactions are observed for the piperazine anion, e.g.HN(CH2CH2)2N- -> -CH2CH2N=CH2 + CH2NH