1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), also known as 1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA), is a lysophosphatidic acid (LPA) analog that contains palmitic acid at the sn-1 position. It is a bioactive lipid molecule that plays a crucial role in various biological processes by binding to G protein-coupled receptors (GPCRs) and mediating a range of cellular responses.
17618-08-5
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Basic information
- Product Name: 1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE(SODIUM SALT)
- Synonyms: 1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE(SODIUM SALT);16:0 LYSO PA SODIUM SALT;1-Palmitoyl Lysophosphatidic Acid (sodium salt) Exclusive;16:0 LPA;16:0 Lyso PA;PA(16:0/0:0)
- CAS NO:17618-08-5
- Molecular Formula: C19H37Na2O7P
- Molecular Weight: 454.45
- EINECS: N/A
- Product Categories: N/A
- Mol File: 17618-08-5.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE(SODIUM SALT)(CAS DataBase Reference)
- NIST Chemistry Reference: 1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE(SODIUM SALT)(17618-08-5)
- EPA Substance Registry System: 1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE(SODIUM SALT)(17618-08-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 17618-08-5(Hazardous Substances Data)
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17618-08-5 Usage
Uses
1. Used in Pharmaceutical Applications:1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt) is used as an enhancer for the action of β-lactam antibiotics, such as ampicillin, piperacillin, and ceftazidime, on various strains of Pseudomonas aeruginosa. This pathogen is associated with pulmonary disease and pneumonia. The enhancement occurs through the binding of both Ca2+ and Mg2+ ions, which can improve the effectiveness of these antibiotics against the pathogen.
2. Used in Diagnostic Applications:
In the medical industry, 1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt) is used as a component in test kits for screening colorectal adenoma. This application aids in the early detection of colorectal cancer, allowing for timely intervention and treatment.
3. Used in Research Applications:
1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt) is also utilized in research settings to study the biological effects of LPA and its role in cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Understanding these processes can lead to the development of new therapeutic strategies for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 17618-08-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,6,1 and 8 respectively; the second part has 2 digits, 0 and 8 respectively.Calculate Digit Verification of CAS Registry Number 17618-08:
(7*1)+(6*7)+(5*6)+(4*1)+(3*8)+(2*0)+(1*8)=115
115 % 10 = 5
So 17618-08-5 is a valid CAS Registry Number.
17618-08-5Upstream product
17618-08-5Downstream Products
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1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE(SODIUM SALT)
