176238-29-2Relevant academic research and scientific papers
Use of O,Se-acetals for radical-mediated phenylseleno group transfer reactions
Renaud, Philippe,Abazi, Sokol
, p. 253 - 258 (2007/10/03)
Ester substituted O,Se-acetals are very efficient radical precursors which can be used for intermolecular formation of C-C bonds via phenylseleno group transfer. The nucleophilic nature of the radical intermediates has been demonstrated and good yields were obtained with alkenes substituted by electron-withdrawing groups. Interestingly, the slow rate of phenylseleno group transfer permitted addition to nonactivated olefins. An intramolecular variant of this reaction provides a simple and efficient access to tetrahydrofuran derivatives.
