176312-96-2Relevant academic research and scientific papers
Dilithiated 3-tosylpropanal dimethyl acetal as β,β-acylvinyl dianion or homoenolate dianion equivalent
Bonete, Pedro,Najera, Carmen
, p. 4111 - 4122 (2007/10/03)
3,3-Dilithio-1,1-dimethoxy-3-tosylpropane (6) reacts with mono and dielectrophiles to give dialkylated products 7 and carbocyclic derivatives 8, respectively. Hydrolysis of the acetal function followed by DBU dehydrosulfinylation of these products affords β,β-disubstituted propenal derivatives 11 and 12. Reductive desulfonylation of compounds 8g-j provides β,β-disubstituted propanal acetals 14.
