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17637-11-5

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17637-11-5 Usage

General Description

(+)-DIBENZOYL-L-TARTARIC ANHYDRIDE, also known as DBTA, is a chiral molecule commonly used as a resolving agent for the separation and analysis of enantiomers in various chemical compounds. It is a white crystalline solid that is sparingly soluble in water and soluble in organic solvents. DBTA is used in high-performance liquid chromatography (HPLC) and gas chromatography (GC) as a chiral derivatizing agent, allowing for the separation of enantiomers with high resolution and efficiency. It is also used as a chiral auxiliary in asymmetric synthesis to control the stereochemistry of reactions and obtain specific chiral products. Additionally, DBTA has been studied for its potential applications in pharmaceutical and chemical industries, particularly in the development of chiral drugs and agrochemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 17637-11-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,6,3 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 17637-11:
(7*1)+(6*7)+(5*6)+(4*3)+(3*7)+(2*1)+(1*1)=115
115 % 10 = 5
So 17637-11-5 is a valid CAS Registry Number.
InChI:InChI=1/C18H12O7/c19-15(11-7-3-1-4-8-11)23-13-14(18(22)25-17(13)21)24-16(20)12-9-5-2-6-10-12/h1-10,13-14H

17637-11-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (+)-DIBENZOYL-L-TARTARIC ANHYDRIDE

1.2 Other means of identification

Product number -
Other names 2S,3S-(D)-dibenzoyltartaric acid anhydride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17637-11-5 SDS

17637-11-5Relevant articles and documents

Discovery of N-Substituted 3-Amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic Acids as Highly Potent Third-Generation Inhibitors of Human Arginase i and II

Van Zandt, Michael C.,Jagdmann, G. Erik,Whitehouse, Darren L.,Ji, Minkoo,Savoy, Jennifer,Potapova, Olga,Cousido-Siah, Alexandra,Mitschler, Andre,Howard, Eduardo I.,Pyle, Anna Marie,Podjarny, Alberto D.

, p. 8164 - 8177 (2019/10/02)

Recent efforts to identify new highly potent arginase inhibitors have resulted in the discovery of a novel family of (3R,4S)-3-amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic acid analogues with up to a 1000-fold increase in potency relative to the current standards, 2-amino-6-boronohexanoic acid (ABH) and N-hydroxy-nor-l-arginine (nor-NOHA). The lead candidate, with an N-2-amino-3-phenylpropyl substituent (NED-3238), example 43, inhibits arginase I and II with IC50 values of 1.3 and 8.1 nM, respectively. Herein, we report the design, synthesis, and structure-activity relationships for this novel series of inhibitors, along with X-ray crystallographic data for selected examples bound to human arginase II.

Single-hole hollow nanospheres from enantioselective self-assembly of chiral AIE carboxylic acid and amine

Li, Dong-Mi,Zheng, Yan-Song

body text, p. 1100 - 1108 (2011/04/12)

Phenylacrylonitrile tartaric acids have been found to enantioselectively self-assemble with an enantiomer of a chiral amine to form either nanofibers or nanospheres that exhibit aggregation-induced emission (AIE). The nanofibers exhibited stronger emission intensity and longer wavelengths of absorption and emission than the nanospheres because of increased π-π conjugation, an effect previously unseen in AIE. When the solvent consists of a mixture of water and THF rather than water and ethanol, the resultant nanospheres have holes. The holes are the result of the dissolution of defects and a decrease in the bending energy. This is in contrast to hole formation from solvents flowing out of the nanospheres, as previously seen. Through control of the water/THF ratio, the size of the holes in the nanospheres can be tuned. Nanospheres with a single hole displayed both higher uptake capacity and larger release speed of the drug naproxen than closed nanospheres. The ability to adjust fluorescent properties of AIE molecules through the preparation of organic single-hole hollow nanospheres has also been investigated along with the implications of the AIE mechanism.

ACYLOXYALKYL CARBAMATE PRODRUGS, METHODS OF SYNTHESIS AND USE

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Page/Page column 441-442, (2008/06/13)

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