176388-95-7

Upstream product

• 1783-96-6 (2R)-aspartic acid 
• 501-53-1 benzyl chloroformate 
• 107-18-6 allyl alcohol 
• 115-11-7 isobutene 

Downstream Products

• 176388-90-2 C₂₄H₃₃NO₈ 
• 176388-91-3 C₂₁H₂₉NO₇ 
• 193156-33-1 (R)-2-Benzyloxycarbonylamino-3-(hydroxy-phenyl-methyl)-succinic acid 1-tert-butyl ester 
• 193140-53-3 (3E,2R)-2-benzyloxycarbonylamino-4-phenyl-3-butenoic acid tert-butyl ester 
• 193140-54-4 (3Z,2R)-2-benzyloxycarbonylamino-4-phenyl-3-butenoic acid tert-butyl ester 
• 193156-34-2 (R)-2-Benzyloxycarbonylamino-3-(hydroxy-phenyl-methyl)-succinic acid 4-allyl ester 1-tert-butyl ester 

Relevant academic research and scientific papers

Synthesis of tripeptide inhibitors of peptidylglycine α-amidating monooxygenase (PAM) containing D- and L-styrylglycine

Both enantiomers of (E)- and (Z)-2-amino-4-phenyl-3-butenoic acids (styrylglycines) 11a,b and 12a,b, were synthesised in non-racemic form, in 7 steps starting from either D- or L-aspartic acid. (E)-Styrylglycine 11a was converted to the tripeptide D-Phe-L-Phe-D-styrylglycine 15, and also to three diastereomeric tripeptides 16-18. All four tripeptides, and both enantiomers of N-acetylstyrylglycine 13a and 13b, were tested as inhibitors of peptidylglycine α-amidating monooxygenase (PAM).