176438-22-5

Basic information

• Product Name: 1-(2-Methyl-oxazolidin-3-yl)-2-phenyl-ethanone
• Synonyms: 1-(2-Methyl-oxazolidin-3-yl)-2-phenyl-ethanone
• CAS NO: 176438-22-5
• Molecular Weight: 205.257
• Mol File: 176438-22-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2-Methyl-oxazolidin-3-yl)-2-phenyl-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Methyl-oxazolidin-3-yl)-2-phenyl-ethanone(176438-22-5)
• EPA Substance Registry System: 1-(2-Methyl-oxazolidin-3-yl)-2-phenyl-ethanone(176438-22-5)

Safety Data

• Hazardous Substances Data: 176438-22-5(Hazardous Substances Data)

Upstream product

• 6269-99-4 N-(2-hydroxyethyl)-2-phenylacetamide 
• 123-63-7 paracetaldehyde 

Downstream Products

• 176438-27-0 2,3-dihydro-3-(2-hydroxyethyl)-2-methyl-5-phenyl-1,3-oxazin-4-one 
• 176438-30-5 2,3-dihydro-3-(2-chloroethyl)-2-methyl-5-phenyl-1,3-oxazin-4-one 

Relevant articles and documents

First synthetic method for the preparation of 6-unsubstituted-2,3-dihydro-1,3-oxazin-4-ones

The first synthetic pathway to synthesize 6-unsubstituted-2,3-dihydro-1,3-oxazin-4-ones is described. The α-formylation of the starting amide and the cyclization of the α-formylamide with a desired aldehyde under acidic conditions gave compounds 5a-h (R = nPr, iPr, cPr, cHex, Ph, CH2Ph, nHex, and R1 = H, Me). This strategy was used with little modification for the preparation of new monocyclic organic nitrates such as 2a-c (2a (R = Ph, R1 = H, and R2 = H), 2b (R = Ph, R1 = H, and R2 = Me), and 2c ( R = H, R1 = Ph, and R2 = H).