176442-70-9Relevant articles and documents
Synthesis and evaluation of 2-aryl-4H-3,1-benzoxazin-4-ones as C1r serine protease inhibitors
Gilmore, John L.,Hays, Sheryl J.,Caprathe, Bradley W.,Lee, Chitase,Emmerling, Mark R.,Michael, Walter,Jaen, Juan C.
, p. 679 - 682 (1996)
A series of 2-aryl-4H-3,1-benzoxazin-4-ones have been synthesized and tested for inhibitory activity against C1r serine protease. Compounds were found that were equipotent and more selective than the reference compound FUT-175.