176506-72-2Relevant academic research and scientific papers
Synthesis of novel metabolically stable analogues of D-myo-inositol 1,4,5-trisphosphate
Fauq, Abdul H.,Zaidi, Javid H.,Wilcox, Robert A.,Varvel, Girlie,Nahorski, Stefan R.,Kozikowski, Alan P.,Erneux, Christophe
, p. 1917 - 1920 (2007/10/03)
Starting from L-quebrachitol, syntheses and biological activities of three novel analogues of the cellular second messenger D-myo-inositol 1,4,5-trisphosphate (IP3), 3-deoxy-3-fluoro-D-myo-inositol 1,4-bisphosphate 5-phosphorothioate (1a), 3-deoxy-3-fluoro-D-myo-inositol 1,5-bisphosphate 4-phosphorothioate (1b), and 3-deoxy-3-fluoro-D-myo-inositol 1-phosphate 4,5-bisphosphorothioate (1c) are described.
