176512-35-9

Upstream product

• 101-59-7 4-amino-4'-nitrodiphenyl sulfide 
• 98-59-9 p-toluenesulfonyl chloride 
• 111453-03-3 4'-nitro-4-N-tosylaminodiphenyl sulfide 
• 176512-29-1 4-(N-propyl-N-tosyl)-amino-4'-nitrodiphenyl sulfide 

Downstream Products

• 176512-42-8 4-(4-nitro-benzenesulfonyl)-N-propyl-aniline 
• 859792-69-1 toluene-4-sulfonic acid-(N-propyl-4-sulfanilyl-anilide) 

Relevant academic research and scientific papers

The iridium-catalyzed synthesis of symmetrically and unsymmetrically alkylated diamines under mild reaction conditions

An iridium catalyst - stabilized by an anionic P,N ligand - was used for the symmetrical and unsymmetrical monoalkylation of para-, meta-, and ortho-benzenediamines. Benzyl and aliphatic alcohols were used as alkylating reagents. 28 derivatives were synthesized. 14 of them are new compounds. Furthermore, the alkylation of the pharmacological important diamine Dapson (dapsone) is described. 14 dapsone derivatives were synthesized among them 9 new compounds. Copyright

New antifolate 4,4'-diaminodiphenyl sulfone substituted 2,4-diamino-5-benzylpyrimidines. Proof of their dual mode of action and autosynergism

New 4,4'-diaminodiphenylsulfone substituted 2,4-diamino-5-benzylpyrimidines were synthesized. These compounds are highly active inhibitors of both bacterial dihydrofolate reductase (DHFR) and dihydropteroic acid synthase (SYN). The simultaneous inhibition