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(2S)-2-(tert-butoxycarbonylamino)-3-(indol-3-yl)propionic acid tert-butyl ester is a bioactive compound belonging to the class of amino acids and peptides. It is a derivative of indole-3-ylpropionic acid, featuring a tert-butyl group attached to the carboxylic acid functional group, which serves as a protective agent in organic synthesis. The indol-3-yl group present in the molecule is known for its diverse pharmacological properties, indicating potential therapeutic applications.

176536-76-8

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176536-76-8 Usage

Uses

Used in Pharmaceutical Industry:
(2S)-2-(tert-butoxycarbonylamino)-3-(indol-3-yl)propionic acid tert-butyl ester is used as a precursor in the synthesis of pharmaceuticals for its potential therapeutic properties. The indole-3-yl group's diverse pharmacological activities make it a valuable component in the development of new drugs targeting various health conditions.
Used in Organic Synthesis:
In the field of organic synthesis, (2S)-2-(tert-butoxycarbonylamino)-3-(indol-3-yl)propionic acid tert-butyl ester serves as an intermediate or building block for the creation of more complex organic molecules. The tert-butyl ester group provides a protected form of the carboxylic acid, facilitating controlled reactions and the synthesis of target compounds with specific functionalities.
Used in Research and Development:
(2S)-2-(tert-butoxycarbonylamino)-3-(indol-3-yl)propionic acid tert-butyl ester is utilized in research and development for studying the structure-activity relationships of indole-containing compounds. Its unique structure allows scientists to explore the effects of the tert-butyl ester and indol-3-yl groups on biological activity, potentially leading to the discovery of new therapeutic agents or synthetic methodologies.

Check Digit Verification of cas no

The CAS Registry Mumber 176536-76-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,6,5,3 and 6 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 176536-76:
(8*1)+(7*7)+(6*6)+(5*5)+(4*3)+(3*6)+(2*7)+(1*6)=168
168 % 10 = 8
So 176536-76-8 is a valid CAS Registry Number.

176536-76-8Downstream Products

176536-76-8Relevant academic research and scientific papers

A simple approach for the synthesis of new pyrimidinyl α-amino acids

Elmarrouni, Abdelatif,Güell, Mireia,Collell, Cristina,Heras, Montserrat

experimental part, p. 612 - 623 (2010/09/14)

A simple synthetic method for the preparation of optically active pyrimidinyl α-amino acids is presented. A nucleophilic ipso-substitution reaction between 2-(benzylsulfonyl)-4-isopropoxypyrimidines and a nucleophilic side chain of several protected natural α-amino acids is investigated to obtain new pyrimidin-2-yl α-amino acids. A detailed optimisation study of this reaction is discussed. Moreover, the selective O-alkylation of 2-(benzylsulfanyl)-4(3H)pyrimidinones with a hydroxylic side chain of some natural α-amino acids under Mitsunobu conditions is studied as a method to prepare new pyrimidin-4-yl α-aminoesters.

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