176548-63-3Relevant academic research and scientific papers
Synthesis and characterization of an oligonucleotide containing the bifurcated nucleobase ω-adenylpropyl uracil
Switzer, Christopher,Prakash, Thazha P.,Ahn, Yoonmo
, p. 815 - 818 (2007/10/03)
A novel bifurcated nucleoside that bears an adenine group trimethylene linked to the 5-position of uracil, 5-(omega-adenylpropyl)-2'-deoxyuridine, has been synthesized and incorporated into a DNA dodecamer. This nucleoside is designed to both intercalate and hydrogen bond when incorporated into an oligonucleotide helix. Initial results of its influence on helix properties are reported.
