17661-50-6 Usage
Chemical Properties
Cetyl esters wax occurs as white to off-white, somewhat translucent
flakes (typically in the range of 5 mm to several millimeters in the
largest dimension), having a crystalline structure and a pearly luster
when caked. It has a faint, aromatic odor and a bland, mild taste.
Production Methods
Cetyl esters wax is prepared by the direct esterification of the
appropriate mixtures of fatty alcohols and fatty acids.
Flammability and Explosibility
Nonflammable
Pharmaceutical Applications
Cetyl esters wax is a stiffening agent and emollient used in creams
and ointments as a replacement for naturally occurring spermaceti.
Cetyl esters wax is hydrophobic and has been proposed as a
suitable component of an ophthalmic gelatin-based, controlledrelease
delivery matrix.
The physical properties of cetyl esters wax vary greatly from
manufacturer to manufacturer owing to differences between the
mixtures of fatty acids and fatty alcohol esters that are used.
Differences between products appear most obviously in the melting
point, which can range from 43–47℃ (USP32–NF27 range) to
51–55°C, depending on the mixture. Materials with a high melting
point tend to contain predominantly cetyl and stearyl palmitates.
Safety Profile
An eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Safety
Cetyl esters wax is an innocuous material generally regarded as
essentially nontoxic and nonirritant.
LD50 (rat, oral): >16 g/kg
storage
Store in a well-closed container in a cool, dry place. Avoid exposure
to excessive heat (above 40℃).
Incompatibilities
Incompatible with strong acids or bases.
Regulatory Status
Included in the FDA Inactive Ingredients Database (topical
preparations). Included in nonparenteral medicines licensed in the
UK. Included in the Canadian List of Acceptable Non-medicinal
Ingredients.
Check Digit Verification of cas no
The CAS Registry Mumber 17661-50-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,6,6 and 1 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 17661-50:
(7*1)+(6*7)+(5*6)+(4*6)+(3*1)+(2*5)+(1*0)=116
116 % 10 = 6
So 17661-50-6 is a valid CAS Registry Number.
InChI:InChI=1/C32H64O2/c1-3-5-7-9-11-13-15-17-18-19-20-22-24-26-28-30-32(33)34-31-29-27-25-23-21-16-14-12-10-8-6-4-2/h3-31H2,1-2H3
17661-50-6Relevant articles and documents
A convenient approach directly from triglycerides toward the producing of thia-wax esters as bio- and chemical raw materials
Y?ld?r?m, Ayhan,K?raylar, Kaan,?ztürk, Serkan
, p. 215 - 230 (2020)
Abstract: Practical and efficient method has been developed for the preparation of novel sulfur-containing esters from triglycerides as potential important industrial and biomaterials. The fact that these unusual compounds are not found in natural sources encourages both academic and industrial communities for their preparation with suitable chemical or enzymatic processes. In general, enzymatic processes requiring more laborious synthesis and product isolation stages. On the other hand, known chemical methods for the preparation of normal wax esters have several drawbacks cited in the present work. Therefore, the chemical method developed in the present study is environmentally benign and suitable for both small- and large-scale syntheses of normal and unusual wax esters. For this purpose, triglycerides were taken to the transesterification reaction in a solvent-free medium with synthetic thia-long-chain alcohols at a ratio of (1:3). In order to catalyze the reaction, newly synthesized bis-imidazole-based metal-free acidic ionic liquid was used and the thia-mono esters were obtained in a fairly short period of time (6?h) with good to excellent yields. The catalyst reuse and large-scale synthesis studies were also carried out. Graphic abstract: [Figure not available: see fulltext.].
PROCESS FOR PRODUCING CARBOXYLIC ACID ESTER AND ESTERIFICATION CATALYST
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Page/Page column 12-13, (2008/06/13)
A process for carboxylic acid ester production by which a carboxylic acid ester comprising an alcohol and a carboxylic acid each having 10 or more carbon atoms can be produced in a high yield. The catalyst used can be reused. The process generates a small amount of wastes and is less apt to pose an environmental problem. Also provided is an esterification catalyst usable in the process. In the esterification of a C10 or higher carboxylic acid and a C10 or higher alcohol, use is made, as a catalyst, of a hydrate of a salt of at least one metal selected among aluminum, gallium, indium, iron, cobalt, nickel, zinc, zirconium, hafnium, and niobium.
