176640-06-5

Upstream product

• 162844-91-9 3-(3-((tert-butyldimethylsilyloxy)methyl)phenyl)-3-(trifluoromethyl)-3H-diazirine 
• 162844-90-8 3-(3-((tert-butyldimethylsilyloxy)methyl)phenyl)-3-(trifluoromethyl)diaziridine 
• 176640-03-2 1-(3-((tert-butyldimethylsilyloxy)methyl)phenyl)-2,2,2-trifluoroethanone 
• 176640-05-4 3-(3-Trifluoromethyl-3H-diazirin-3-yl)-benzoyl chloride 
• 176640-04-3 3-[3-hydroxymethylphenyl]-3-trifluoromethyl-3H-diazirine 
• 103978-12-7 [(3-bromobenzyl)oxy](tert-butyl)dimethylsilane 
• 15852-73-0 (3-Bromophenyl)methanol 

Downstream Products

• 176640-07-6 N-[2-(3,4-Dichloro-phenyl)-4-oxo-butyl]-N-methyl-3-(3-trifluoromethyl-3H-diazirin-3-yl)-benzamide 

Relevant academic research and scientific papers

A non-peptide photoactivatable antagonist for mapping the antagonist binding site of the tachykinin NK2 receptor

SR 48968, N-Methyl-N-[4-(4-acetamido-4-phenylpiperidinyl)-2S-(3,4-dichlorophenyl ) butyl]benzamide is a potent and selective non-peptidic antagonist of the NK2 receptor. A photoactivatable analogue containing a diazirine moiety also binds with high affinity. This compound is potentially useful for identifying residues at the antagonist binding site of the NK2 receptor.