176696-77-8Relevant articles and documents
Use of cyclohexene epoxides in the preparation of carbocyclic nucleosides
Mikhailov, Sergey N.,Blaton, Norbert,Rozenski, Jef,Balzarini, Jan,De Clercq, Erik,Herdewijn, Piet
, p. 867 - 878 (1996)
A simple route towards 4,4-dihydroxymethyl-cyclohexane nucleosides has been developed. The structure of 4,4-dihydroxymethyl-1-(thymin-1-yl)- cyclohexane was confirmed by X-ray analysis. The synthesized compounds were inactive against all viruses tested.
Two convergent approaches toward novel carbocyclic C-nucleosides
Nencka, Radim,Sala, Michal,Dejmek, Milan,Drainsky, Martin,Holy, Antonin,Hebabecky, Hubert
scheme or table, p. 4119 - 4130 (2011/02/22)
Two convergent methodologies for construction of novel carbocyclic C-nucleosides allowing the syntheses of derivatives with uracil heterobase substituted at the position C-5 as well as C-6 were developed. The crucial step of the first methodology was the