17672-27-4

Basic information

• Product Name: 4-hydrazinylbenzonitrile
• Synonyms: 4-hydrazinylbenzonitrile
• CAS NO: 17672-27-4
• Molecular Formula: C₇H₇N₃
• Molecular Weight: 133.15
• Mol File: 17672-27-4.mol
• Article Data: 13

Chemical Properties

• Melting Point: 91-93 °C
• Boiling Point: 325.9 °C at 760 mmHg
• Flash Point: 150.9 °C
• Appearance: /
• Density: 1.19
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: 4.11±0.20(Predicted)
• CAS DataBase Reference: 4-hydrazinylbenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydrazinylbenzonitrile(17672-27-4)
• EPA Substance Registry System: 4-hydrazinylbenzonitrile(17672-27-4)

Safety Data

• Hazardous Substances Data: 17672-27-4(Hazardous Substances Data)

Usage

General Description

4-hydrazinylbenzonitrile is a chemical compound with the molecular formula C7H6N4. It is a derivative of benzonitrile with a hydrazine functional group attached to the benzene ring. 4-hydrazinylbenzonitrile is used in organic synthesis and pharmaceutical research as a building block for the synthesis of various compounds, including hydrazide derivatives. 4-hydrazinylbenzonitrile is known to have potential application as a pesticide and herbicide due to its bioactivity. It is also being investigated for its potential as an anti-tumor agent and as a precursor for the synthesis of drugs. 4-hydrazinylbenzonitrile is known for its high purity and stability, making it an important reagent in laboratory research.

Upstream product

• 2863-98-1 4-hydrazinobenzonitrile hydrochloride 
• 873-74-5 4-Aminobenzonitrile 

Downstream Products

• 1354828-66-2 tert-butyl 2-(4-cyanophenyl)diazene-1-carboxylate 
• 92722-14-0 tert-butyl 2-(4-nitrophenyl)diazenecarboxylate 
• 586-78-7 para-nitrophenyl bromide 
• 13677-42-4 4-bromo-N-(4-methoxyphenyl)aniline 
• 2765-22-2 2'.5'-Dichlor-4-nitro-biphenyl 
• 17849-31-9 2-chloro-3-(4-nitrophenyl)propionitrile 
• 5332-96-7 1-(4-nitrophenyl)propan-2-one 
• 92-93-3 1-phenyl-4-nitrobenzene 
• 13444-01-4 methyl 2-(4-nitrophenyl)azocarboxylate 
• 1354828-51-5 tert-butyl 2-(4-(4-(2-(ethylamino)ethyl)phenoxy)phenyl)azocarboxylate 
• 1354828-75-3 tert-butyl 2-(4-(4-fluorophenoxy)phenyl)azoxycarboxylate 
• 1354828-74-2 4'-nitro-2-phenoxy-1,1'-biphenyl 
• 128924-06-1 4'-phenoxy-4-nitrobiphenyl 
• 1354828-72-0 4'-(4-fluorophenoxy)-2,5-dimethoxybiphenyl 

Relevant articles and documents

Visible-light-mediated phosphonylation reaction: formation of phosphonates from alkyl/arylhydrazines and trialkylphosphites using zinc phthalocyanine

In this work, we developed a ligand- and base-free visible-light-mediated protocol for the photoredox syntheses of arylphosphonates and, for the first time, alkyl phosphonates. Zinc phthalocyanine-photocatalyzed Csp2-P and Csp3-P bond formations were efficiently achieved by reacting aryl/alkylhydrazines with trialkylphosphites in the presence of air serving as an abundant oxidant. The reaction conditions tolerated a wide variety of functional groups.

SUBSTITUTED SULFONYL HYDRAZIDES AS INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY

The present invention relates to substituted sulfonyl hydrazides that have the ability to inhibit lysine biosynthesis via the diaminopimelate pathway in certain organisms. As a result of this activity these compounds can be used in applications where inhibition of lysine biosynthesis is useful applications of this type include the use of the compound as herbicides and/or anti- bacterial agents.

Synthesis and biological evaluation of benzimidazole phenylhydrazone derivatives as antifungal agents against phytopathogenic fungi

A series of benzimidazole phenylhydrazone derivatives (6a-6ai) were synthesized and characterized by 1H-NMR, ESI-MS, and elemental analysis. The structure of 6b was further confirmed by single crystal X-ray diffraction as (E)-configuration. All the compounds were screened for antifungal activity against Rhizoctonia solani and Magnaporthe oryzae employing a mycelium growth rate method. Compound 6f exhibited significant inhibitory activity against R. solani and M. oryzae with the EC50 values of 1.20 and 1.85 μg/mL, respectively. In vivo testing demonstrated that 6f could effectively control the development of rice sheath blight (RSB) and rice blast (RB) caused by the above two phytopathogens. This work indicated that the compound 6f with a benzimidazole phenylhydrazone scaffold could be considered as a leading structure for the development of novel fungicides.