176723-00-5

Basic information

• Product Name: Benzoic acid (4R,5S)-5-[(1R,2S)-1-tert-butoxycarbonylamino-2-(tert-butyl-dimethyl-silanyloxy)-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester
• CAS NO: 176723-00-5
• Molecular Weight: 609.833
• Mol File: 176723-00-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid (4R,5S)-5-[(1R,2S)-1-tert-butoxycarbonylamino-2-(tert-butyl-dimethyl-silanyloxy)-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid (4R,5S)-5-[(1R,2S)-1-tert-butoxycarbonylamino-2-(tert-butyl-dimethyl-silanyloxy)-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester(176723-00-5)
• EPA Substance Registry System: Benzoic acid (4R,5S)-5-[(1R,2S)-1-tert-butoxycarbonylamino-2-(tert-butyl-dimethyl-silanyloxy)-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester(176723-00-5)

Safety Data

• Hazardous Substances Data: 176723-00-5(Hazardous Substances Data)

Upstream product

• 176722-99-9 (4S,5S)-5-[(1R,2S)-1-tert-Butoxycarbonylamino-2-(tert-butyl-dimethyl-silanyloxy)-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid methyl ester 
• 176722-98-8 (3aS,4R,6aS)-4-[(S)-(tert-Butyl-dimethyl-silanyloxy)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methyl]-2,2-dimethyl-6-oxo-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid tert-butyl ester 
• 157720-16-6 tert-butyl (R)-2-((S)-((tert-butyldimethylsilyl)oxy)((R)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 141293-15-4 (1'S,2R,4''R)-2-[(2,2-dimethyl-[1,3]dioxolan-4-yl)hydroxymethyl]-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylic acid tert-butyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 176723-01-6 Benzoic acid (4R,5S)-5-[(1R,2S)-1-tert-butoxycarbonylamino-2-(tert-butyl-dimethyl-silanyloxy)-3-oxo-propyl]-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester 

Relevant articles and documents

Divergent synthesis of 3-amino-3-deoxy- and 4-amino-4-deoxyhexoses

A new efficient synthesis of 3-amino-3-deoxy-D-altrose (13), 3-amino-3-deoxy-L-allose (17), and 4-amino-4-deoxy-D-talose (21) from 2,3-O-isopropylidene-D-glyceraldehyde (6) using N-(tert-butoxycarbonyl)-2-(tert-butyldimethylsiloxy)pyrrole (TBSOP) as homologative nucleophile is described. The procedure highlights the merits of densely functionalized homochiral heptonolactam 9 as a key divergent intermediate.