17673-28-8Relevant academic research and scientific papers
Protecting group free synthesis of glycosyl thiols from reducing sugars in water; application to the production of N-glycan glycoconjugates
Alexander,Lim,Amso,Brimble,Fairbanks
supporting information, p. 2152 - 2156 (2017/03/20)
Glycosyl thiols may be accessed from the corresponding reducing sugars in water without recourse to any sugar projecting groups by way of a DMC mediated reaction with thioacetic acid in the presence of base, and hydrolysis of the anomeric thioacetate. Glycosyl thiols produced by this method may be used to access glycoconjugates, such as glycopeptides by use of the thiol-ene click reaction.
BIOSYNTHESIS OF A D-GLUCOSYL POLYISOPRENYL DIPHOSPHATE IN PARTICULATE PREPARATIONS OF MICROCOCCUS LYSODEIKTICUS
Yamazaki, Tatsumi,Laske, Douglas W.,Herscovics, Annette,Warren, Christopher D.,Jeanloz, Roger W.
, p. 159 - 170 (2007/10/02)
Particulate fractions of Micrococcus lysodeikticus incubated with UDP-D-glucose incorporated radioactivity into a chloroform-methanol-soluble, low-mol. wt. compound, and into a polymer.The low-mol. wt. compound consisted of a glucolipid that was extremely labile to mild acid hydrolysis with the formation of D-glucose, and to mild alkali, yielding 14C-labeled α-D-glucopyranose 1,2-phosphate and D-glucose 2-phosphate.The labeled glucolipid was eluted from a DEAE-cellulose column at a salt concentration higher than that required by synthetic ficaprenyl (D-glucopyranosyl phosphate), and it migrated more slowly than the latter compound in t.l.c.Formation of glucolipid was stimulated by exogenous ficaprenyl phosphate, but not by C55-dolichyl phophate.These results suggest that the glucolipid has the characteristic properties of a polyisoprenyl glucosyl diphosphate.
