176747-25-4

Upstream product

• 10457-16-6 2',3',5,-tris-O-(trimethylsilyl)uridine 
• 58-96-8 uridine 
• 154153-59-0 N³-(2-thiobenzoylethyl)uridine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 84592-34-7 1-t-butylthiohydrazine-1,2-dicarboxmorpholide 

Downstream Products

• 154153-62-5 5'-O-(4,4'-dimethoxytrityl)-3'-O-(tert-butyldimethylsilyl)-N³-ethyluridine tert-butyl disulfide 
• 154153-60-3 5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-N³-ethyluridine tert-butyl disulfide 

Relevant academic research and scientific papers

Synthesis of a disulfide stabilized RNA hairpin

An N-3 ethylthiol-modified uridine has been synthesized and incorporated through solid-phase phosphoramidite chemistry at the 5'- and 3'-termini of an RNA hairpin to provide increased conformational stability via a disulfide cross-link.

Design, synthesis, and analysis of yeast tRNAPhe analogs possessing intra- and interhelical disulfide cross-links

Disulfide cross-links have been site-specifically incorporated into unmodified yeast tRNAPhe by total chemical synthesis. One cross-link is between positions 1 and 72 in the amino-acid acceptor stem, and it was prepared by replacing G1 and C72