176789-93-8

Upstream product

• 2227-29-4 chlorodiisopropylsilane 
• 583-53-9 2,3-dibromobenzene 

Downstream Products

• 181874-55-5 1-Diisopropylsilanyl-2-(diisopropyl-trimethylsilanylethynyl-silanyl)-benzene 
• 176789-94-9 1,2-bis(chloroisopropylsilanyl)benzene 

Relevant academic research and scientific papers

Photochemical functionalization of C60 with cyclosilanes and cyclogermane

The photochemical reaction of 3,4-benzo-1,2-disilacyclobutene 1 with C60 afforded stable 1:1 adduct 2 with C(2v) symmetry. The photochemical reaction of cyclotetrasilane 4a with C60 afforded adducts 5a and 6a, the latter was obtained from a rearrangement of the cyclotetrasilane unit. Similarly, cyclotetragermanes, 4c, gave 5c and the rearranged product 6c. In the case of cyclotrasilane 4b, only the rearranged product 6b was obtained in high yield. The structure of all compounds were determined by spectroscopic methods, including 29Si-1H HMBC hetero nuclear shift correlation experiments.

Steric and Electronic Effects in Cyclic Alkoxyamines - Synthesis and Applications as Regulators for Controlled/Living Radical Polymerization

The synthesis of new six- and seven-membered cyclic alkoxyamines bearing ethyl groups at the α-N position of the alkoxyamines is described. The key step in the synthesis of the sterically hindered six-membered cyclic alkoxyamines is a Wadsworth-Horner-Emm

Reagent and process for protecting active groups

Silylating reagents having a group other than a divalent oxygen separating two silyl groups provide regioselective protection of reactive groups under robust conditions, such as basic conditions used in alkylation, acylation and deoxygenation. In particular, silylating reagents having a group other than oxygen separating two silyl groups are useful for protecting two hydroxy groups of a ribonucleic or deoxyribonucleic acid. Alkylation of a 2′-hydroxy group of a ribonucleoside protected with the inventive silylating agents in the presence of an excess of a mild hindered base such as sodium HMDS may be carried out without protecting the exocyclic amine and oxo functionalities of nucleobases.

Palladium-catalyzed reactions of 1,1,2,2-tetraethyl-and 1,1,2,2-tetra(isopropyl)-3,4-benzo-1,2-disilacyclobut-3-ene with alkynes

The reactions of 3,4-benzo-1,1,2,2-tetra(isopropyl)-1,2-disilacyclobut-3-ene (2) with acetylene, phenylacetylene, 1-hexyne, and o-tolylacetylene in the presence of tetrakis(triphenylphosphine)palladium gave the respective 5,6-benzo-1,4-disilacyclohexa-2,5-dienes 3-6. Similar reactions of 2 with mesitylacetylene, trimethylsilylacetylene, and dimethylphenylsilylacetylene afforded 1-alkynyl(diisopropylsilyl)-2-(diisopropylsilyl)benzenes 7-9 arising from sp-hybridized C-H bond activation of acetylenes. The reactions of 3,4-benzo-1,1,2,2-tetraethyl-1,2-disilacyclobut-3-ene with mesitylacetylene, trimethylsilylacetylene, and dimethylphenylsilylacetylene produced 5,6-benzo-1,4-disilacyclohexa-2,5-dienes 10-12 as the sole product. The stoichiometric reaction of 2 with tetrakis(triphenylphosphine)palladium gave a yield of 3,4-benzo-2,2,5,5-tetra(isopropyl)-1-pallada-2,5-disilacyclopent-3-ene (A), arising from insertion of a palladium species into a silicon-silicon bond in 2.