176849-72-2Relevant academic research and scientific papers
ω-haloalkylphosphoryl compounds: Synthesis and properties
Ragulin
, p. 1928 - 1937 (2013/06/05)
A general method of the synthesis of ω-haloalkylphosphoryl compounds was developed, a series of compounds of phosphonic and phosphine oxide type were synthesized. The ability of some ω-haloalkylphosphonates to undergo intramolecular cyclization into the corresponding 1,2-oxaphospholane and 1,2-oxaphosphorine was investigated depending on the solvent polarity, the presence of halogen ions in the solution, and temperature. Tetrahydrofuran was chosen as one of the most suitable solvents for the alkylation of CH acids with ω-haloalkylphosphoryl compounds.
Synthesis and biological activity of dialkylamino-substituted phosphine oxides
Yarkevich,Petrova,Bachurin
, p. 1659 - 1664 (2013/02/23)
A series of dialkylamino-substituted phosphine oxides was synthesized and their physiological activity was studied. Pleiades Publishing, Ltd., 2012.
OXYPHOSPHORANE ANIONS AS NUCLEOPHILES IN INTRAMOLECULAR DISPLACEMENT REACTIONS
Aksnes, Gunnar
, p. 55 - 62 (2007/10/02)
The present paper reports a kinetic study of alkaline decomposition of four bromoalkyltriphenyl phosphonium bromides with the bromo-substituent in 3-, 4-, 5, and 6-positions, respectively (hereafter designated 3Br-P, 4Br-P, 5Br-P, and 6Br-P), together with the alkaline decomposition of 1,1,4,4-tetrabenzyl-1,4-diphosphoniocyclohexane dibromide (designated 2P).The very high rates of decomposition of 3Br-P and 2P are in accordance with an easy formation of five-membered oxaphospholane ring intermediates through participation of oxyphosphorane anions in intramolecular displacement reactions, with carbon in 3Br-P, and with phosphorus in the neighbouring phosphonium cation of 2P. Key words: Oxyphosphorane anions, bromoalkyltriphenyl phosphonium bromides, 1,1,4,4-tetrabenzyl-1,4-diphosphoniocyclohexane dibromides.
