17686-43-0

Basic information

• Product Name: decyl cyanoacetate
• Synonyms: decyl cyanoacetate;Cyanoacetic acid decyl ester
• CAS NO: 17686-43-0
• Molecular Formula: C13H23NO2
• Molecular Weight: 225.32722
• EINECS: 241-670-6
• Mol File: 17686-43-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 269.4°Cat760mmHg
• Flash Point: 121.3°C
• Appearance: /
• Density: 0.938g/cm³
• Vapor Pressure: 0.00726mmHg at 25°C
• Refractive Index: 1.445
• CAS DataBase Reference: decyl cyanoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: decyl cyanoacetate(17686-43-0)
• EPA Substance Registry System: decyl cyanoacetate(17686-43-0)

Safety Data

• Hazardous Substances Data: 17686-43-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H23NO2/c1-2-3-4-5-6-7-8-9-12-16-13(15)10-11-14/h2-10,12H2,1H3

Upstream product

• 112-29-8 1-bromo dodecane 
• 105-56-6 ethyl 2-cyanoacetate 
• 112-30-1 1-Decanol 

Downstream Products

• 89269-06-7 Decyl 3-ethoxy-2-cyanoacrylate 

Relevant articles and documents

Palladium-Catalyzed Direct Arylation of C(sp3)-H Bonds of α-Cyano Aliphatic Amides

Pd(OAc)2-catalyzed arylation of C(sp3)-H bonds in α-cyano-α-methyl aliphatic amides is achieved in the presence of 8-aminoquinoline, as a removable directing group, using Mn(OAc)2 and Na2CO3. The current strategy enables the placement of an aryl/heteroaryl group at the β-position of α-cyano aliphatic acids for the first time. Wide functional group tolerance and easily accessible starting materials provide an efficient protocol for the synthesis of arylated α-cyano amides. Furthermore, the synthetic utility of the products has been demonstrated by their efficient conversions to medicinally important α,α-dialkylated acid and β-amino acid derivatives.