176860-59-6

Basic information

• Product Name: [1,1'-BIPHENYL]-4-ETHANIMIDAMIDE, N-HYDROXY
• Synonyms: [1,1'-BIPHENYL]-4-ETHANIMIDAMIDE, N-HYDROXY
• CAS NO: 176860-59-6
• Molecular Formula: C₁₄H₁₄N₂O
• Molecular Weight: 0
• Mol File: 176860-59-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [1,1'-BIPHENYL]-4-ETHANIMIDAMIDE, N-HYDROXY(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-BIPHENYL]-4-ETHANIMIDAMIDE, N-HYDROXY(176860-59-6)
• EPA Substance Registry System: [1,1'-BIPHENYL]-4-ETHANIMIDAMIDE, N-HYDROXY(176860-59-6)

Safety Data

• Hazardous Substances Data: 176860-59-6(Hazardous Substances Data)

Upstream product

• 31603-77-7 4-biphenylacetonitrile 

Relevant articles and documents

Catalyst-free, one-pot strategy to access 3-substituted-5-amino-1,2,4-thiadiazoles in water

A protocol has been devised for the synthesis of 3-substituted 5-amino-1,2,4-thiadiazoles utilizing isothiocyanates, amidoximes and water as an eco-friendly solvent. The strategy involves consecutive C?N and S?N bonds formation in a one-pot reaction under

Antihyperglycemic activity of novel substituted 3H-1,2,3,5-oxathiadiazole 2-oxides

A series of substituted 3H-1,2,3,5-oxathiadiazole-2-oxides (6) was prepared and tested for antihyperglycemic activity in the db/db mouse, a model for type 2 (non-insulin dependent) diabetes mellitus. The oxathiadiazoles 6 were synthesized by a two-step sequence: treatment of a substituted acetonitrile (4) with hydroxylamine to give the corresponding amidoxime (5) and cyclization with thionyl chloride to yield 6. In terms of potency, the 2-naphthalenylmethyl group (as in compound 3) was found to be the optimal substituent in this series. Compound 3 was approximately 5 times more potent than ciglitazone (1).