176907-01-0

Basic information

• Product Name: ((4aR,4bR,8aS,8bS)-5-Benzyloxycarbonylmethyl-2,4,6,8-tetraoxo-decahydro-1,3,5,7-tetraaza-biphenylen-1-yl)-acetic acid benzyl ester
• CAS NO: 176907-01-0
• Molecular Weight: 520.499
• Mol File: 176907-01-0.mol

Chemical Properties

• CAS DataBase Reference: ((4aR,4bR,8aS,8bS)-5-Benzyloxycarbonylmethyl-2,4,6,8-tetraoxo-decahydro-1,3,5,7-tetraaza-biphenylen-1-yl)-acetic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: ((4aR,4bR,8aS,8bS)-5-Benzyloxycarbonylmethyl-2,4,6,8-tetraoxo-decahydro-1,3,5,7-tetraaza-biphenylen-1-yl)-acetic acid benzyl ester(176907-01-0)
• EPA Substance Registry System: ((4aR,4bR,8aS,8bS)-5-Benzyloxycarbonylmethyl-2,4,6,8-tetraoxo-decahydro-1,3,5,7-tetraaza-biphenylen-1-yl)-acetic acid benzyl ester(176907-01-0)

Safety Data

• Hazardous Substances Data: 176907-01-0(Hazardous Substances Data)

Upstream product

• 176907-02-1 benzyl 2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetate 
• 100-51-6 benzyl alcohol 
• 4113-97-7 uracilacetic acid 

Relevant articles and documents

Synthesis and Structure of (Carboxymethyl)-Functionalized Cyclobuta-Fused Uracil Dimers

Herein, we report a convenient method for the preparation of four benzyl-ester-protected, (carboxymethyl)-functionalized cyclobuta-fused uracil dimers 1-4, including the desired cis-cisoid-cis,syn-configured isomer 1, a compound which is suitable for the preparation of catalytic antibodies, synthetic receptors, and model compounds, required for the investigation of the DNA-lesion, recognition step and DNA-repair mechanisms. A comprehensive structure determination of each isomer by 1H-NMR, and in the case of the cis-cisoid-cis,syn-and the cis-transoid-cis-cis,syn-dimers by X-ray crystal-structure analysis, is also provided.

Zur DNA-Reparatur durch das Enzym DNA-Photolyase: Synthese von Flavin enthaltenden Modellverbindungen

Keywords: DNA-Reparatur; Elektronentransfer; Flavine; Nucleobasen