176907-06-5

Basic information

• Product Name: 1,2-Benzenediamine, N-(2-methoxyethyl)-4,5-dimethyl-
• CAS NO: 176907-06-5
• Molecular Formula: C11H18N2O
• Molecular Weight: 194.277
• Mol File: 176907-06-5.mol

Chemical Properties

• CAS DataBase Reference: 1,2-Benzenediamine, N-(2-methoxyethyl)-4,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenediamine, N-(2-methoxyethyl)-4,5-dimethyl-(176907-06-5)
• EPA Substance Registry System: 1,2-Benzenediamine, N-(2-methoxyethyl)-4,5-dimethyl-(176907-06-5)

Safety Data

• Hazardous Substances Data: 176907-06-5(Hazardous Substances Data)

Upstream product

• 6972-71-0 4,5-dimethyl-2-nitrobenzenamine 
• 1799-80-0 4,5-dimethyl-2-nitro-N-(trifluoroacetyl)aniline 
• 3171-45-7 4,5-dimethyl-1,2-phenylenediamine 
• 6482-24-2 2-Bromoethyl methyl ether 
• 176907-05-4 N-(3′-oxabut-1′-yl)-4,5-dimethyl-2-nitroaniline 

Relevant articles and documents

Discrimination of redox-responsible biomolecules by a single molecular sensor

A new application of a fluorescent sensor (PyDPA) for the discrimination of redox-responsible molecules is reported. Nicotinamide adenine dinucleotide/nicotinamide adenine dinucleotide phosphate (NAD +/NADP+) and flavin mononucleotid

Thiourea-enhanced flavin photooxidation of benzyl alcohol

Upon irradiation, flavin oxidises 4-methoxybenzyl alcohol to the corresponding aldehyde using aerial O2 as the terminal oxidant. We have observed that this reaction is significantly accelerated by the presence of thiourea. A series of thiourea-functionalised flavins has been prepared from flavin isothiocyanates and their photocatalytic efficiencies have been monitored by NMR. The alcohol photooxidation proceeds rapidly and cleanly with high turnover numbers of up to 580, exceeding previously reported performances. A likely mechanistic rationale for the more than 30-fold acceleration of the photo-redox reaction by thiourea has been derived from spectroscopic, electrochemical, and kinetic studies. Thus, thiourea acts as an electron-transfer mediator for the initial photooxidation of 4-methoxybenzyl alcohol by the excited flavins. This mechanism has similarities to electron-relay mechanisms in flavoenzymes, for which cysteine sulfenic acid intermediates are proposed. The observation that thiourea mediates flavin photo-redox processes is valuable for the design of more sophisticated photocatalysts based on Nature's best redox chromophore.

Investigation of flavin-containing DNA-repair model compounds

Irradiation of DNA with UV-B light causes the formation of mutagenic DNA lesions such as cis-syn and trans-syn cyclobutane pyrimidine dimers. DNA photolyases are flavin-dependent repair enzymes which directly revert the mutagenic cis-syn pyrimidine dimers

Zur DNA-Reparatur durch das Enzym DNA-Photolyase: Synthese von Flavin enthaltenden Modellverbindungen

Keywords: DNA-Reparatur; Elektronentransfer; Flavine; Nucleobasen