176959-92-5Relevant articles and documents
Asymmetric syntheses, opioid receptor affinities, and antinociceptive effects of 8-amino-5,9-methanobenzocyclooctenes, a new class of structural analogues of the morphine alkaloids
Schultz, Arthur G.,Wang, Aihua,Alva, Carlos,Sebastian, Alice,Glick, Stanley D.,Deecher, Darlene C.,Bidlack, Jean M.
, p. 1956 - 1966 (1996)
Several 8-amino-5,9-methanobenzocyclooctenes have been prepared by asymmetric organic synthesis techniques. Opioid receptor affinity studies have revealed the virtual absence of enantioselectivity for receptor binding, particularly at the μ-receptor, for