176962-79-1

Basic information

• Product Name: 4-bromo-2-<1-trimethylsiloxy-1-phenylmethyl>thiophene
• CAS NO: 176962-79-1
• Molecular Weight: 341.344
• Mol File: 176962-79-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-bromo-2-<1-trimethylsiloxy-1-phenylmethyl>thiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-<1-trimethylsiloxy-1-phenylmethyl>thiophene(176962-79-1)
• EPA Substance Registry System: 4-bromo-2-<1-trimethylsiloxy-1-phenylmethyl>thiophene(176962-79-1)

Safety Data

• Hazardous Substances Data: 176962-79-1(Hazardous Substances Data)

Upstream product

• 591-51-5 phenyllithium 
• 18791-75-8 4-Bromothiophen-2-aldehyde 

Downstream Products

• 1027146-19-5 5-(Phenyl-trimethylsilanyloxy-methyl)-thiophene-3-sulfonyl chloride 
• 1026277-35-9 5-(Phenyl-trimethylsilanyloxy-methyl)-thiophene-3-sulfonic acid amide 
• 155954-69-1 5-<1-hydroxy-1-phenylmethyl>-3-thiophenesulfonamide 

Relevant articles and documents

5-Substituted 3-thiophenesulfonamides as carbonic anhydrase inhibitors

A series of 5-substituted 3-thiophenesulfonamides was prepared from 4-bromo-2-thiophene carboxaldehyde. Several of these compounds inhibited carbonic anhydrase II in vitro at concentrations of less than 10 nM. In the ex vivo assay, these compounds have inhibitory values in the 25-81% range. Additionally, none of these compounds exhibit sensitization potential as determined by in vitro measurement of cysteine reactivity.