176966-37-3

Basic information

• Product Name: 3-Oxa-7-azabicyclo[4.1.0]heptane, 7-acetyl-4-methoxy-, [1R-(1alpha,4beta,6alpha)]- (9CI)
• Synonyms: 3-Oxa-7-azabicyclo[4.1.0]heptane, 7-acetyl-4-methoxy-, [1R-(1alpha,4beta,6alpha)]- (9CI)
• CAS NO: 176966-37-3
• Molecular Formula: C8H13NO3
• Molecular Weight: 171.19372
• Product Categories: ACETYLGROUP
• Mol File: 176966-37-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Oxa-7-azabicyclo[4.1.0]heptane, 7-acetyl-4-methoxy-, [1R-(1alpha,4beta,6alpha)]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Oxa-7-azabicyclo[4.1.0]heptane, 7-acetyl-4-methoxy-, [1R-(1alpha,4beta,6alpha)]- (9CI)(176966-37-3)
• EPA Substance Registry System: 3-Oxa-7-azabicyclo[4.1.0]heptane, 7-acetyl-4-methoxy-, [1R-(1alpha,4beta,6alpha)]- (9CI)(176966-37-3)

Safety Data

• Hazardous Substances Data: 176966-37-3(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 176966-36-2 (1R,4R,6R)-4-methoxy-3-oxa-7-azabicyclo[4.1.0]heptane 
• 17676-20-9 methyl 2-deoxy-β-D-erythro-pentopyranoside 
• 22900-10-3 2-deoxy-D-ribose 

Relevant articles and documents

An efficient stereoselective synthesis of the amino sugar component (E ring) of calicheamicin γ1(I)

A simple, efficient, stereoselective synthesis of the methyl 2,4-dideoxy-4-(ethylamino)-3-O-methyl-β-L-threo-pentopyranoside 2, corresponding to the E monosaccharide unit (E ring) of calicheamicin 1, is described. The synthetic procedure utilizes the methyl 2-deoxy-β-D-ribopyranoside 3 as the enantiopure starting material and the acid methanolysis of the intermediate activated aziridine 12 to give the desired amino sugar 2 in 6 steps and in satisfactorily high overall yield (60%). No separation stage is necessary at any point of the synthetic process.