176967-12-7

Basic information

• Product Name: 2-Amino-3-(1-benzyl-1H-indol-3-yl)-4-tert-butoxycarbonyl-pentanedioic acid 5-tert-butyl ester 1-ethyl ester
• Synonyms: 2-Amino-3-(1-benzyl-1H-indol-3-yl)-4-tert-butoxycarbonyl-pentanedioic acid 5-tert-butyl ester 1-ethyl ester
• CAS NO: 176967-12-7
• Molecular Weight: 536.668
• Mol File: 176967-12-7.mol

Chemical Properties

• CAS DataBase Reference: 2-Amino-3-(1-benzyl-1H-indol-3-yl)-4-tert-butoxycarbonyl-pentanedioic acid 5-tert-butyl ester 1-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-3-(1-benzyl-1H-indol-3-yl)-4-tert-butoxycarbonyl-pentanedioic acid 5-tert-butyl ester 1-ethyl ester(176967-12-7)
• EPA Substance Registry System: 2-Amino-3-(1-benzyl-1H-indol-3-yl)-4-tert-butoxycarbonyl-pentanedioic acid 5-tert-butyl ester 1-ethyl ester(176967-12-7)

Safety Data

• Hazardous Substances Data: 176967-12-7(Hazardous Substances Data)

Upstream product

• 10511-51-0 1-Benzylindole-3-carboxaldehyde 
• 176967-10-5 (E)-3-(1-Benzyl-1H-indol-3-yl)-2-nitro-acrylic acid ethyl ester 
• 541-16-2 t-butyl malonate 
• 176967-11-6 3-(1-Benzyl-1H-indol-3-yl)-2-tert-butoxycarbonyl-4-nitro-pentanedioic acid 1-tert-butyl ester 5-ethyl ester 

Relevant articles and documents

Synthesis of 3-amino-4-indolyl-2-piperidones: Tryptophan-derived pseudodipeptides

(αR,3R*,4R*)-N-(2-Acetoxy-1-phenylethyl)-3- allyloxycarbonylamino-4-(1-benzyl-3-indolyl)-2-piperidone (1), a pseudodipeptide which contains a conformationally restricted analogue of tryptophan has been synthesized from anhydride (2) and (R)-(-)-phenylglycinol (3).

Conformationally restricted analogues of tryptophan: Synthesis of chiral 3-amino-4-indolyl-2-piperidones

The {Trp-phenylglycinol} pseudodipeptide (αR,3R*,4R*)-N-(2-acetoxy-1-phenylethyl)-3-amino-4-indolyl-2-piperi done 33 has been synthesized by condensation of the 3-amino-substituted anhydride 30 with (R)-(-)-phenylglycinol followed by reduction of the resulting imide.