176972-39-7Relevant academic research and scientific papers
Comparative kinetic studies on the alkaline hydrolysis of halogen substituted isocoumarins
Ahmad, H. Badaruddin,Malana, M. Aslam,Yousaf, Muhammad,Rehan, Muhammad,Abbas, Mazhar,Abaidullah
experimental part, p. 381 - 386 (2010/11/03)
Kinetics of the hydrolysis of 3-(2'-chloro-6'-fluorobenzyl)isocoumarin (1), 3-(4'-fluorophenyl)isocoumarin (3), 3-(2'-fluorophenyl)isocoumarin (5), 3-(2'-chlorophenyl)isocoumarin (7), and 3-(4'-chlorophenyl)isocoumarin (9) were studied spectrophotometrica
Synthesis of some new 3-(chlorophenyl)isocoumarins and their conversion to 3,4-dihydro derivatives
Rama, Nasim H.,Iqbal,Rauf,Rao, Muhammad I.,Zamani,Raza, Abdul R.
, p. 338 - 341 (2007/10/03)
Condensation of homophthalic acid 4 with chlorobenzoyl chlorides 5a-c yields 3-(chlorophenyl)isocoumarins 6a-c which on alkaline hydrolysis give the keto-acids 7a-c. (dl)-3-(Chlorophenyl)-3,4-dihydroisocoumarins 10a-c have been obtained by the reduction of 7a-c to racemic hydroxyacids 9a-c followed by cyclodehydration using acetic anhydride.
