177-17-3

Basic information

• Product Name: 6-Azaspiro[4.5]decane
• Synonyms: 6-Azaspiro[4.5]decane
• CAS NO: 177-17-3
• Molecular Formula: C9H17N
• Molecular Weight: 139.23798
• Mol File: 177-17-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-Azaspiro[4.5]decane(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Azaspiro[4.5]decane(177-17-3)
• EPA Substance Registry System: 6-Azaspiro[4.5]decane(177-17-3)

Safety Data

• Hazardous Substances Data: 177-17-3(Hazardous Substances Data)

Usage

General Description

6-Azaspiro[4.5]decane, also known as spirocyclohexane and bicyclo[3.3.1]nonane, is a chemical compound with the molecular formula C9H17N. It is a highly strained, bridged bicyclic compound containing a nitrogen atom in the spiro center. 6-Azaspiro[4.5]decane is an important building block in organic synthesis and is used in the pharmaceutical industry for the synthesis of various biologically active compounds. It is also known for its unique strained structure, which makes it a useful probe in studies of molecular reactivity and stability. Despite its synthetic importance and interesting physical properties, 6-Azaspiro[4.5]decane is relatively unexplored in terms of its potential applications and properties, making it a promising area for further research.

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Two novel fatty acids with cPLA 2 inhibitory activity, pinnaic acid and tauro-pinnaic acid, were isolated from the Okinawan bivalve Pinna muricata. Their structures, including the relative stereochemistry at C5, C9, C13 and C14, were elucidated by extensive 2D NMR spectroscopic analysis.detailed

Synthesis of a 6-azaspiro[4.5]decane related to halichlorine and the pinnaic acids09/28/2019

Sulfone 15, derived from d-glutamic acid, and aldehyde 23, made by diastereoselective alkylation, were linked and elaborated into enamine sulfone 33. This underwent 5-exo radical cyclization to 34, which was desulfonylated to (-)-35, a compound that represents the spirobicyclic core of halichlo...detailed