1771-18-2Relevant articles and documents
Microwave-assisted phenothiazines preparation by thionation of diphenylamines
Filip, Sorin V.,Silberg, Ioan A.,Surducan, Emanoil,Vlassa, Mircea,Surducan, Vasile
, p. 337 - 345 (1998)
A preparation in 'dry media' of phenothiazine derivatives by thionation of diphenylamines using microwave-activation is presented. This method allowed the preparation of 2,4,6,8-tetra-tert-butyl-10H-phenothiazine 2e, the first 2,4,6,8-tetra-substituted derivative of this heterocycle, practically inaccessible by other thionation procedure.
Improved synthesis of 2-methoxyphenothiazine
Ruan, Jian-Cheng,Zhang, Tao,Wang, Shuai,Liu, Jin-Qiang,Qian, Chao,Chen, Xin-Zhi
, p. 438 - 441 (2012/07/03)
A procedure for synthesis of 2-methoxyphenothiazine (1) has been developed, starting from resorcinol and aniline by condensation, following methylation and cyclization. p-Toluenesulfonic acid and polysubstituted aromatics were employed as the catalyst of condensation and the solvent of cyclization, respectively, to improve the yield. The use of parallel experiments, statistical experimental design, and multivariate modeling made the total yield of the procedure as high as 74.2%. Copyright
Synthesis of hydrazones derived from 2-substituted-10-carboxyphenothiazine hydrazides
Tsitsa,Psarrea-Sandris,Sandris
, p. 1661 - 1663 (2007/10/02)
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