1773-46-2

Usage

Uses

Used in Chemical Research and Analysis:
(1E)-1-(2-chlorobenzylidene)-2-(2,4-dinitrophenyl)hydrazine is used as a research compound for studying its chemical properties and potential applications in organic chemistry. Its unique structure allows researchers to explore its reactivity and interactions with other compounds, contributing to the advancement of chemical knowledge.
Used in Organic Synthesis:
As an intermediate in the synthesis of various organic compounds, (1E)-1-(2-chlorobenzylidene)-2-(2,4-dinitrophenyl)hydrazine plays a crucial role in the development of new chemical entities. Its presence in the synthesis process can lead to the formation of novel compounds with potential applications in various industries, such as pharmaceuticals, materials science, and agrochemicals.
Used in Pharmaceutical Industry:
(1E)-1-(2-chlorobenzylidene)-2-(2,4-dinitrophenyl)hydrazine is used as a building block for the development of new pharmaceutical compounds. Its unique structure and reactivity can be leveraged to create new drug candidates with potential therapeutic applications. (1E)-1-(2-chlorobenzylidene)-2-(2,4-dinitrophenyl)hydrazine's potential as a precursor in drug synthesis makes it valuable in the search for innovative treatments and medications.
Used in Materials Science:
In the field of materials science, (1E)-1-(2-chlorobenzylidene)-2-(2,4-dinitrophenyl)hydrazine can be used as a component in the development of new materials with specific properties. Its incorporation into polymers, coatings, or other materials can lead to the creation of materials with improved characteristics, such as enhanced stability, reactivity, or selectivity.
Used in Agrochemical Industry:
(1E)-1-(2-chlorobenzylidene)-2-(2,4-dinitrophenyl)hydrazine can also find applications in the agrochemical industry, where it may be used as a precursor for the synthesis of new pesticides, herbicides, or other agricultural chemicals. Its unique structure and reactivity can contribute to the development of more effective and environmentally friendly agrochemicals.

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 119-26-6 (2,4-dinitro-phenyl)-hydrazine 
• 34403-62-8 N-(o-chlorobenzylideneamino)phthalimide 
• 33472-12-7 [(2-Chloro-phenyl)-hydroxy-methyl]-phosphonic acid dibutyl ester 
• 17849-38-6 2-Chlorobenzyl alcohol 

Relevant academic research and scientific papers

Synthesis, structural characterization, and antioxidant activities of 2,4-dinitrophenyl-hydrazone derivatives

Thirty-two derivatives of 2,4-dinitro phenylhydrazone 1-32 were synthesized by one step reaction and characterized by spectroscopic techniques such as EI-MS and 1H-NMR. Compounds 1-32 were screened for their in vitro antioxidant activities. DPPH radical s

Structure-Reactivity correlation in the oxidation of substituted benzaldehydes by tetraethylammonium chlorochromate

Oxidation of 36 monosubstituted benzaldehydes by tetraethylammonium chlorochromate in dimethyl sulphoxide, leads to the formation of corresponding benzoic acids. The reaction is of first order with respect to chlorochromate and aldehydes. The reaction is promoted by H+; the H+ dependence has the form kobs = a + b[H+]. The oxidation of duteriated benzaldehyde exhibits substantial primary kinetic isotope effect. The reaction was studied in 19 different organic solvents and the effect of solvent was analyzed using Taft's and Swain's multiparametric equations. The rates of the oxidation of para- and meta-substituted benzaldehydes showed excellent correlation in terms of Charton's triparametric LDR equation, whereas the oxidation of ortho-substituted benzaldehydes were correlated well with tetraperametric LDRS equation. The oxidation of para-substituted benzaldehydes is more susceptible to the delocalized effect than is the oxidation of ortho- and meta- substituted compounds, which display a greater dependence on the field effect. The positive value of h suggests the presence of an electron-deficient reaction centre in the rate-determining step. The reaction is subjected to steric acceleration by the orthosubstituents. A suitable mechanism has been proposed.

Kinetics and Mechanism of the Oxidation of Substituted Benzylamines by N-Chlorosuccinimide

The oxidation of ortho-, meta-, and para-substituted benzylamines by N-chlorosuccinimide (NCS), to the corresponding benzaldehydes, is first-order with respect to NCS and the amine.The pH dependence of the reaction rate suggests that the unprotonated benzylamine is the reductant.There is no effect of added succinimide.NCS itself has been postulated as the reactive oxidising species.The oxidation of benzylamine exhibited a substantial primary kinetic isotope effect (kH/kD=6.20).The rates of oxidation of the meta- and para-substituted benzylamines were separately correlated in Taft and Swain's dual substituent parameter equations.For the para-substituted compounds, the best correlation is obtained with ?I and ?R+ values; meta-substituted compounds correlate with ?I and ?R0 values.The reaction constants have negative values.The oxidation rates of the ortho-substituted compounds yield an excellent correlation in a triparametric equation involving Taft's ?I and ?R+ values and Charton's steric parameter, V.A mechanism involving transfer of a hydride ion from the amine to the oxidant in the rate-determining step is proposed.

Preparation and Use of Tetra-n-butylammonium Per-ruthenate (TBAP reagent) and Tetra-n-propylammonium Per-ruthenate (TPAP reagent) as New Catalytic Oxidants for Alcohols

Tetra-n-butylammonium per-ruthenate (Bun4N)(RuO4) and tetra-n-propylammonium per-ruthenate (Prn4N)(RuO4), with N-methylmorpholine N-oxide, function as mild catalitic oxidants for the high yield conversion of alcohols to aldehydes and ketones and are competitive with more conventional reagents.

A New Ring Opening Reaction of N-Aminophthalimide Hydrazones

Araldehyde hydrazones III of N-aminophthalimide underwent rapid ring opening reactions initiated by the addition of excess base to their refluxing methanolic solutions.The products were conveniently isolated through liquid-liquid extraction as the stable