1773-51-9

Usage

General Description

The chemical 1-Naphthalenecarbaldehyde 2,4-dinitrophenyl hydrazone is a derivative of naphthalene and is used as a reagent in chemical reactions. It is a yellow to orange crystalline compound that is commonly used to detect the presence of aldehydes. When reacted with aldehydes, it forms a yellow precipitate that can be used to qualitatively determine the presence of the functional group in organic compounds. It is also used in analytical chemistry for the identification and quantification of aldehydes in various samples. Additionally, it has potential applications in the synthesis of other organic compounds and in research settings.

Upstream product

• 66-77-3 1-naphthaldehyde 
• 119-26-6 (2,4-dinitro-phenyl)-hydrazine 

Downstream Products

• 66-77-3 1-naphthaldehyde 

Relevant academic research and scientific papers

Unveiling of a smartphone-mediated ratiometric chemosensor towards the nanomolar level detection of lethal CN?: combined experimental and theoretical validation with the proposition of a molecular logic circuitry

A promising naphthalene-functionalized ratiometric chemosensor (E)-1-((naphthalen-5-yl) methylene)-2-(2,4-dinitrophenyl) hydrazine (DNMH) is unveiled in the present work. DNMH demonstrates brisk discernible colorimetric response from yellow to red in the presence of CN?, a lethal environmental contaminant, in a near-perfect aqueous medium with a LOD of 278 nM. The “key role marker” controlling the electrochemical and non-covalent H-bonding interaction between DNMH and CN? is through the commendable role of acidic -NH functionalities. Kinetic studies reveal a pseudo second order reaction rate and the formation of an unprecedented photostable adduct. The negative value of ΔG as evaluated from ITC substantiates the spontaneity of the DNMH?CN? interaction. The sensing mechanism was further reinforced with state-of-the-art theoretical investigations, namely DFT, TDDFT and Fukui indices (FIs). Moreover, the proposition of a reversible multi-component logic circuitry implementing Boolean functions in molecular electronics has also been triggered by the turn-over spectrophotometric response of the ditopic ions CN? and Cd2+. The cytotoxicity of DNMH towards Bacillus thuringiensis and Escherichia coli is successfully investigated via the MTT assay. Impressively, “dip stick” and “easy to prepare” test paper device and silica gel-based solid-phase CN? recognition validate the on-site analytical application of DNMH. Furthermore, the involvement of a synergistic approach between ‘chemistry beyond the molecule’ and ‘engineering’ via an exquisitely implemented smartphone-assisted colorimetric sensory prototype makes this work unprecedented among its congeners and introduces a new frontier in multitudinous material-based functional product development.

Synthesis, structural characterization, and antioxidant activities of 2,4-dinitrophenyl-hydrazone derivatives

Thirty-two derivatives of 2,4-dinitro phenylhydrazone 1-32 were synthesized by one step reaction and characterized by spectroscopic techniques such as EI-MS and 1H-NMR. Compounds 1-32 were screened for their in vitro antioxidant activities. DPPH radical s

Synthesis, binding ability, and cell cytotoxicity of fluorescent probes for l-arginine detection based on naphthalene derivatives: Experiment and theory

Inspired by biological related parts, Schiff base derivatives and functional groups of chemical modification can provide efficient detection method of amino acids. Therefore, we have designed and prepared 4 compounds based on Schiff base derivatives invol