177326-60-2Relevant articles and documents
Synthesis and cytotoxic activity of new 9-substituted camptothecins
Dallavalle, Sabrina,Rocchetta, Daniela Granza,Musso, Loana,Merlini, Lucio,Morini, Gabriella,Penco, Sergio,Tinelli, Stella,Beretta, Giovanni Luca,Zunino, Franco
, p. 2781 - 2787 (2008/12/22)
A series of novel 9-substituted camptothecins derived from 9-formylcamptothecin were synthesized. The aldehyde was obtained from 10-hydroxycamptothecin or, better, by total synthesis. The compounds showed antiproliferative activity higher than that of the