177337-91-6Relevant academic research and scientific papers
Phenylimidazolidine preparation process
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, (2008/06/13)
A subject of the invention is a preparation process for the products of formula (I): STR1 in which R1 and R2 represent in particular hydrogen, cyano, halogen or amino,R3 represents in particular hydrogen or hydroxyl alkyl, R4 and R5 represent in particular optionally substituted alkyl, X and y represent oxygen or sulphur, characterized in that a product of formula (A): STR2 is prepared in which W represents a halogen atom or a hydantoin derivative, which is subjected to various reactions in order to obtain the products of formula (I), all their isomers and their salts.
METHOD OF INDUCING ANTIANDROGENIC ACTIVITY USING IMIDAZOLIDINES SUBSTITUTED WITH A HETEROCYCLE
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, (2008/06/13)
Novel imidazoles of the formula STR1 wherein the substituents are as defined in the disclosure and their non-toxic, pharmaceutically acceptable addition salts with acids and bases having antiandrogenic activity.
