17742-46-0

Basic information

• Product Name: 3,4,5-trimethoxyphenyl acetate
• CAS NO: 17742-46-0
• Molecular Formula: C₁₁H₁₄O₅
• Molecular Weight: 226.2259
• Mol File: 17742-46-0.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 319.2°C at 760 mmHg
• Flash Point: 139.1°C
• Density: 1.136g/cm³
• Vapor Pressure: 0.000345mmHg at 25°C
• Refractive Index: 1.49
• CAS DataBase Reference: 3,4,5-trimethoxyphenyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4,5-trimethoxyphenyl acetate(17742-46-0)
• EPA Substance Registry System: 3,4,5-trimethoxyphenyl acetate(17742-46-0)

Safety Data

• Hazardous Substances Data: 17742-46-0(Hazardous Substances Data)

Upstream product

• 642-71-7 3,4,5-trimethoxyphenol 
• 127-09-3 sodium acetate 
• 1136-86-3 methyl (3,4,5-trimethoxyphenyl) ketone 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 634-36-6 1,2,3-trimethoxybenzene 
• 33035-41-5 2-(diacetoxyiodo)mesitylene 
• 15233-65-5 2,6-dimethoxy-1,4-hydroquinone 
• 2754-27-0 trimethylsilyl acetate 
• 108-24-7 acetic anhydride 

Downstream Products

• 1355483-74-7 2-(4-bromophenyl)-5,6,7-trimethoxy-4H-chromen-4-one 
• 1355483-83-8 C₁₈H₁₇BrO₅ 
• 1392217-71-8 5-hydroxy-3-(2-hydroxybenzyl)-6,7-dimethoxychroman-4-one 
• 1392217-70-7 2'-hydroxy-5,6,7-trimethoxy-3-benzylchroman-4-one 
• 55085-47-7 5,6,7-trimethoxycoumarin 
• 1401431-14-8 C₂₅H₁₆N₂O₅ 
• 1401431-13-7 C₂₃H₁₆I₂O₅ 
• 1401431-12-6 C₂₃H₁₆Br₂O₅ 
• 1401431-11-5 C₂₃H₁₆Cl₂O₅ 
• 1401431-10-4 C₂₃H₁₆F₂O₅ 
• 1401431-18-2 C₂₃H₁₆N₂O₉ 

Relevant articles and documents

An efficient synthesis of 8-substituted Odoratine derivatives by the Suzuki coupling reaction

An efficient method for the preparation of 8-substituted odoratine [(3-(3 ′, 4 ′-methylenedioxyphenyl)-5,6,7-trimethoxyisoflavone] derivatives, structurally similar to glaziovianin A, a known cytotoxic substance, has been described.

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Inventors of the present invention synthesized natural homoisoflavonoid portulacanone D (compound 6) isolated from Portulaca oleracea L (POL). An ability to inhibit NO production in LPS-induced RAW 264.7 macrophages was assessed as an indicator of anti-inflammatory activity. The tested portulacanone D did not show clear cytotoxicity and inhibited NO production in the RAW 264.7 macrophages in a concentration dependent manner. The portulacanone D exhibits 92.5% of NO production inhibition at 10 andmu;M and has an IC50 value of 2.09 andmu;M. The finding has additional correlation with the suppressed expression of iNOS induced by LPS. According to the information obtained from the study of the present invention, the portulacanone D can be used in the development of anti-inflammatory drugs targeting NO production.COPYRIGHT KIPO 2019